2020
DOI: 10.2217/pmt-2019-0039
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Transition from Acute to Chronic Pain: Where Cells, Systems and Society Meet

Abstract: Current treatments for chronic pain are often ineffective. At the same as searching for novel therapeutics, there is growing interest in preventing acute pain becoming chronic. While the field is still in its infancy, its knowledge base is increasingly expanding. Certainly, biomedical factors, for example, the type of tissue damage, are important but they are often not modifiable. Psychosocial risk factors (e.g., thoughts and beliefs about pain, mood, social support, workplace problems) are modifiable. There i… Show more

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Cited by 17 publications
(20 citation statements)
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“…Average FABQ-PA scores at baseline were moderate (10.91, SD 4.59), with 20% (60/300) participants presenting with an FABQ-PA score above 15 points (18.84, SD 2.44), a threshold that has been associated with poorer prognosis [ 8 , 12 ]. FABQ-PA scores decreased over time ( p < 0.001, Table 2 ), with a 39.5% reduction at end of program (mean difference 4.32 points, 95% CI 0.93 to 11.3, p < 0.001), and 83.3% (40/48) of the participants who scored above 15 at baseline ending the program below this score.…”
Section: Resultsmentioning
confidence: 99%
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“…Average FABQ-PA scores at baseline were moderate (10.91, SD 4.59), with 20% (60/300) participants presenting with an FABQ-PA score above 15 points (18.84, SD 2.44), a threshold that has been associated with poorer prognosis [ 8 , 12 ]. FABQ-PA scores decreased over time ( p < 0.001, Table 2 ), with a 39.5% reduction at end of program (mean difference 4.32 points, 95% CI 0.93 to 11.3, p < 0.001), and 83.3% (40/48) of the participants who scored above 15 at baseline ending the program below this score.…”
Section: Resultsmentioning
confidence: 99%
“…Additionally, influencing fear-avoidant behaviors has been reported as a tool to prevent pain from becoming chronic [ 8 , 12 , 71 , 72 ]. The reductions herein observed for FABQ-PA (39.5%) are slightly lower that those reported by Storheim et al , [ 63 ] and Campello et al , [ 64 ] for a combination of exercise and CBT in subacute low back pain (59.9% improvement), but baseline values were lower in our sample (10.9 vs 14.2).…”
Section: Discussionmentioning
confidence: 99%
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“…Traditionally, it includes relaxation therapy, activity pacing, sleep hygiene, scheduling pleasant activity, identifying and modifying cognitive distortions (Barrett et al, 2020). CBT has also shown promise in preventing acute pain conversion to chronic pain (Glare et al, 2020). Pain catastrophizing is a response style that impacts the outcomes of chronic pain patients.…”
Section: Non-pharmacological Therapiesmentioning
confidence: 99%
“…Pain is one such adverse effect and all modalities of cancer treatment—surgery, chemotherapy, radiation therapy (RT), transplants and immunotherapy—can be painful. Acute pain becomes chronic in approximately 10–20% cases [ 3 ], causing distress and disability that reduces the quality of life long term.…”
Section: Introductionmentioning
confidence: 99%