Transition in the Higher-order Structure of DNA in Aqueous Solution

Modulation of DNA conformation in electrolytic nanodroplets

“…In a pure aqueous solution, long-chain DNA is randomly coiled. 44 The electrostatic repulsion induced by the negative charges between their base pairs is helpful to prevent it from bending. 40,45 In the ionic solution, positive ions are adsorbed around the DNA, shielding the negative charge of DNA, which alters the electrostatic interactions between the DNA strands.…”