Transition metal complexes of 5-bromosalicylidene-4-amino-3-mercapto-1,2,4-triazine-5-one: Synthesis, characterization, catalytic and antibacterial studies

Abstract

Transition metal complexes of 5-bromosalicylidene-4-amino-3- mercapto-1,2,4-triazine-5-one with metal precursors, such as Cu(II), Ni(II), Co(II) and Pd(II), were synthesized and characterized by physicochemical and spectroscopic techniques. All the complexes are of the ML type. Based on analytical, spectral data and magnetic moments, the Co(II) and Ni(II) complexes were assigned octahedral geometries, while the Cu (II) and Pd(II) complexes square planar. A study on the catalytic oxidation of benzyl alcohol, cyclohexanol, cinnamyl alcohol, 2-propanol and 2- methyl-1-propanol was performed with N-methylmorpholine-N-oxide (NMO) and molecular oxygen as co-oxidants. All the complexes and their parent organic moiety were screened for their biological activity on several pathogenic bacteria and were found to possess appreciable bactericidal properties.

Coordination compounds of some transition metal ions with new Schiff base ligand derived from dibenzoyl methane. Structural characterization, thermal behavior, molecular structure, antimicrobial, anticancer activity and molecular docking studies

“…Metal complexes of Schiff base ligands have gained considerable attention as the results of their spectroscopic properties and remarkable antifungal, antibacterial and antitumor activities applications . Nowadays Schiff bases are considered privileged ligands due to their ability to stabilize many different metals in various oxidation states, controlling the performance of metals in a large variety of useful applications in industrial fields together with their important roles in catalysis and organic synthesis …”

Synthesis, characterization, in silico, and in vitro biological screening of coordination compounds with 1,2,4-triazine based biocompatible ligands and selected 3d-metal ions

“…The coordination sites of ligand to the metal ions can be best studied by comparing the IR spectra of ligand and complexes ( Figure 3 ), Table 2 . Complexation alters the stretching frequency of the C=N bond suggesting the coordination of ligand to metal ions through azomethine nitrogen atom [ 29 ]. The disappearance of peaks due to υ(N–H) at 3169 cm ─1 and υ(C=S) at 1199 cm ─1 and the appearance due to υ(C–S) around 600–700 cm ─1 suggested the existence of thiol-thione tautomerism which is also confirmed by NMR studies.…”

Synthesis and characterization of a new ligand (E)-2-(4-((2-(2-((2-hydroxynaphthalen-1-yl) methylene) hydrazinyl) thiazol-4-yl) amino) phenyl) acetic acid, and its complexes

“…The band at (1255cm -1 ) was evidence of stretching vibration of the (C-O) bond. (3033cm -1 ) band was an indicative of the aromatic C-H , where is (2981-2935cm¹) band belongs to the aliphatic C-H, and (2907cm -1 )to the C-H thiazol ring [12][13][14][15]as shown in table (2)..…”