2017
DOI: 10.26850/1678-4618eqj.v36.3.2011.p31-36
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Transition Metal Complexes of Omeprazole An Anti-Ulcerative Drug

Abstract: Omeprazole (OME) is a proton pump inhibitor (PPI). PPI’s have enabled to improve the treatment of various acidpeptic disorders. OME is a weak base and it can form several complexes with transition and non-transitions metal ions. In the present paper, we are describing series of trantion metal complexes of omeprazole i.e.,5-methoxy-2[(4methoxy-3,5dimethyl-2-pyridinyl)methylsulfinyl]–1H–benzimidazole with CuII, MnII, CoII, NiII, FeII, ZnII and HgII. These complexes were characterized by elemental analysis, molar… Show more

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“…The λ max of OMZ was observed at 257 and 300 nm, and at 263 and 293 nm for 8-hydroxyquinoline. These absorption peaks are due to n→π* andπ→π* electronic transition [23]. The electronic spectra of the synthesized mixed ligand complexes were in the range of 300-350 nm.…”
Section: Dpph Radical Scavenging Activitymentioning
confidence: 93%
“…The λ max of OMZ was observed at 257 and 300 nm, and at 263 and 293 nm for 8-hydroxyquinoline. These absorption peaks are due to n→π* andπ→π* electronic transition [23]. The electronic spectra of the synthesized mixed ligand complexes were in the range of 300-350 nm.…”
Section: Dpph Radical Scavenging Activitymentioning
confidence: 93%