Transition Metal‐Free Decarboxylative CH Bond Functionalization

Abstract

This article highlights the recent advances in metal‐free decarboxylative coupling reactions for the CH bond functionalization leading to CC or CX bond formation. The ready availability of a variety of carboxylic acids and extrusion of CO 2 as the only by‐product are some of the attributes, which make this coupling approach sustainable and environmentally benign as compared to the conventional coupling reactions. This article features three major routes for nonmetallic decarboxylative CH bond functionalization viz. (i) oxidative CH bond functionalization; (ii) visible‐light CH bond functionalization, and (iii) electrochemical CH bond functionalization.