Transition-metal mediated carbon–sulfur bond activation and transformations: an update

Abstract

<p>This review summarizes the advances in transition-metal-catalyzed cross-coupling <italic>via</italic> carbon–sulfur bond activation and cleavage since late 2012 as an update of the critical review published in early 2013 (<italic>Chem. Soc. Rev.</italic>, 2013, <bold>42</bold>, 599–621).</p>

Gold(I)-Catalyzed Synthesis of 3-Sulfenyl Pyrroles and Indoles by a Regioselective Annulation of Alkynyl Thioethers

“… 6 , 7 The increasing number of C–S functionalization methods renders them potentially useful substrates for further elaboration. 8 The prospective utility of sulfenylated pyrrole and indole products combined with the diversity of reaction pathways that can be accessed from (benz)isoxazoles identified them as ideal systems for probing the wider utility of alkynyl thioethers in nitrenoid-based annulations.…”

An Acyclic Diaminocarbene Complex of Platinum Formed by Desulfurization of 1,3‐Bis(3‐methylpyridin‐2‐yl)thiourea

“…Whereas a conventional N,S‐chelated compound 2 of thiourea with cis ‐PtCl 2 is formed in aprotic dichloromethane, the conversion in methanol leads to a desulfurized material 3 with a tridentate (py)N−N(H)CN(H)−N(py) diaminocarbene ligand and one coordinated and one „free“ chloride. While we refrain from mechanistic speculation it is tempting to associate the latter reaction in protic CH 3 OH with hydrodesulfurization (HDS), [68] including C−S cleavage, [69] which are not uncommon processes involving platinum.…”

Nickel-catalyzed asymmetric reductive arylation of α-chlorosulfones with aryl halides

“…Sulfones are not only important functional units in synthetic chemistry 1 but also unique compounds that have been widely studied in medicinal chemistry. 2 Among them, a number of alkyl sulfones are FDA-approved drugs ( e.g.…”