Transitional cell carcinoma in urachal cyst

Abstract

A 33-year-old male patient with abdominal mass for a year was referred to our institute. CT scan with intravenous contrast was performed, which showed a cystic lesion at the infraumbilical region, beneath the anterior abdominal wall with the presence of solid enhancing mass apposed to the anterior wall of the cyst. We suggested a diagnosis of urachal cyst with possibility of malignancy. On surgical exploration, the cystic mass was found superior to and separate from the urinary bladder dome. Histopathology revealed transitional cell carcinoma in a urachal cyst.

Efficacy of Keratin AE1/AE3 Staining in Evaluating Resection Margins of a Urachal Remnant and Improving Surgical Precision and Outcomes: A Case Report

“…At our department, surgical intervention is typically warranted for urachal remnant patients exhibiting symptoms after adolescence, particularly those with lesions localized between the umbilical fossa and the abdominal wall, and without concurrent urological issues. While cases of urachal cancer have been reported previously [4][5][6][7], the condition is rare, underscoring the importance of ensuring the complete removal of urachal epithelium during surgery to mitigate the risk of cancer. While histopathological examination has traditionally been utilized to assess residual urachal epithelium at the resection margin, limitations have been observed, with instances where definitive exclusion of urachal epithelial cells using hematoxylin and eosin (HE) staining alone has been challenging.…”