Transitional Cell Carcinoma Manifesting as Acute Cor Pulmonale

DHILLON, SAMJOT SINGH; Singh, Digvijay; DASS, BHAGWAN; SCHAUB, CARL R.

doi:10.1097/00007611-200110000-00018

Cited by 5 publications

(1 citation statement)

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“…In many cases, patients may develop liver failure before symptomatic PTE, especially with primary lesion anatomically distant from the chest or liver, such as bladder cancer. To the best of our knowledge, symptomatic microscopic PTE from TCC has been reported in 11 cases, and only 5 cases presented without pulmonary hypertension (Table) (6)(7)(8)(9)(10)(11)(12)(13)(14). However, we should pay attention to new lung metastases in patients receiving long-term chemotherapy for liver metastases.…”

Section: Discussionmentioning

confidence: 98%

Unusual Development of Pulmonary Tumor Embolism from Controlled Liver Metastases of Transitional Cell Carcinoma: An Autopsy Case

et al. 2016

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Clinicians generally suspect pulmonary tumor embolism (PTE) with uncontrolled carcinomas which often spread to lungs. We, however, experienced an autopsy case of diffuse microscopic PTE despite controlled liver metastases of transitional cell carcinoma (TCC). A 66-year-old man with progressing respiratory symptoms showed almost normal chest findings on computed tomography. Although liver metastases were successfully shrunk by chemotherapy, the patient died from aggressive respiratory failure. An autopsy revealed small pulmonary vessels showing diffuse tumor emboli. TCC can cause PTE even if liver metastases are controlled. We must therefore be aware that PTE can manifest as respiratory symptoms without any computed tomography findings.

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Section: Discussionmentioning

confidence: 98%