Transitional Zone Index and Intravesical Prostatic Protrusion in Benign Prostatic Hyperplasia Patients: Correlations according to Treatment Received and Other Clinical Data

Abstract

PurposeThe aim of this research was to assess the value of the transitional zone index (TZI) and intravesical prostatic protrusion (IPP) from transrectal ultrasonography in evaluating the severity and progression of disease by analyzing the relationship between the 2 parameters and symptoms, clinical history, and urodynamics in benign prostatic hyperplasia (BPH) patients undergoing different treatment.Materials and MethodsA total of 203 patients receiving medication and 162 patients who underwent transurethral resection of the prostate because of BPH were enrolled in this retrospective analysis. The clinical history and subjective and objective examination results of all patients were recorded and compared after being classified by TZI and IPP level. Linear regression was used to find correlations between IPP, TZI, and urodynamics.ResultsThe 2 parameters were found to differ significantly between patients receiving medication and patients undergoing surgical therapy (p<0.05). PSA, maximum flow rate (Qmax), detrusor pressure at Qmax (PdetQmax), and the bladder outlet obstruction index (BOOI) differed according to various TZI levels (p<0.05). In addition, the voiding symptom score, Qmax, and BOOI of subgroups with various IPP levels were also significantly different (p<0.05). Both TZI and IPP had significant effects on Qmax, BOOI, and PdetQmax (p<0.05) and the incidence of acute urinary retention (p=0.000).ConclusionsThe results demonstrated that both TZI and IPP had favorable value for assessing severity and progression in patients with BPH. Further studies are needed to confirm whether the two parameters have predictive value in the efficacy of BPH treatment and could be considered as factors in the selection of therapy.

Association between Single Nucleotide Polymorphism of Vitamin D Receptor Gene FokI Polymorphism and Clinical Progress of Benign Prostatic Hyperplasia

“…Q max⁡ and PSA appear not to be good indicators for progression of BPH. In the current study, we found that the control group has smaller prostate volume and lower level of I-PSS than the progression group ( P < 0.05), which agreed with the results from other studies [ 2 , 21 ].…”

Prostatic Peripheral Zone Thickness: What is Normal on Magnetic Resonance Imaging?

“…This compares with mean volume of 10.6 cc in a Japanese screening study of asymptomatic men over age 55 years [16] and 9-15 cc in a population screening of Chinese men 40-70 years of age [17]. However, TZV reported in most studies in the United States and Asia in men of average age over 55 years ranges from 21-26 cc in subjects with TPV averaging 35-49 cc [6, 7, 15, 18,19,11,20,21]. Since TZV is known to correlate to TPV our results come as no surprise [22,4].…”

Role of Transition Zone Index in the Prediction of Clinical Benign Prostatic Hyperplasia

“…It is demonstrated that TZI accurately predicts acute urinary retention in BPH patients, and that it might be helpful to decide for medical therapy or surgery (16,17), and that it has a PPV for the progression and severity of the disease (18), and that it predicts the necessity of TUR-P procedure (19). It is confirmed that TZI and TZV predict the efficiency of TUR-P procedure pre-operatively (7), and that more than 60% of the TZV should be resected to benefit from TUR-P (20).…”