2006
DOI: 10.1001/archinte.166.4.418
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Transitions Between Frailty States Among Community-Living Older Persons

Abstract: Background: Little is known about the natural course of frailty. We performed a prospective study to determine the transition rates between frailty states and to evaluate the effect of the preceding frailty state on subsequent frailty transitions. Methods: We studied 754 community-living persons, aged 70 years or older, who were nondisabled in 4 essential activities of daily living. Frailty, assessed every 18 months for 54 months, was defined on the basis of weight loss, exhaustion, low physical activity, musc… Show more

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Cited by 851 publications
(494 citation statements)
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“…14 This suggests that health promotion interventions may be more effective when targeted at less frail populations. Indeed, positive outcomes of preventative home visits (multidimensional visits addressing medical, functional, psychosocial and/or environmental problems and resources) by nurses on mortality rates appear to be greater for younger-old rather than older-old populations.…”
Section: Clinical Frailty Scalementioning
confidence: 99%
“…14 This suggests that health promotion interventions may be more effective when targeted at less frail populations. Indeed, positive outcomes of preventative home visits (multidimensional visits addressing medical, functional, psychosocial and/or environmental problems and resources) by nurses on mortality rates appear to be greater for younger-old rather than older-old populations.…”
Section: Clinical Frailty Scalementioning
confidence: 99%
“…For each of 3 transitions (baseline to 6 months, 6 to 12 months, and 12 to 30 months), proportions were estimated for FI score decrease (≥0.02 decrease in FI score), stable FI score (change of <0.02), FI score increase (≥0.02 increase in FI score), deaths, and withdrawals. 32 A change of 0.02 was used as it corresponds with slightly more than a gain or loss of one deficit and is similar to the threshold used by other researchers. 33 To compare age, sex, and treatment group differences associated with change over time, we fitted FI scores to linear mixed models with a random intercept.…”
Section: Resultsmentioning
confidence: 99%
“…Numerous publications have looked at frailty longitudinally in general populations: characterizing frailty transitions, 22,32,33,40 examining potential predictors of transitions, [41][42][43] testing interventions to limit worsening frailty, 44 and comparing static versus dynamic frailty measures to predict functional decline. 45 However, few have looked longitudinally at a cohort of patients with cardiovascular disease.…”
Section: Discussionmentioning
confidence: 99%
“…It is possible to recover from frailty to prefrailty and nonfrailty conditions, respectively [10]. This makes the adoption of preventive measures attractive.…”
Section: Introductionmentioning
confidence: 99%