Abstract. Aerosols and clouds affect atmospheric radiative processes and climate in many complex ways and still pose the largest uncertainty in current estimates of the Earth’s changing energy budget. Airborne in-situ sensors such as the Cloud, Aerosol, and Precipitation Spectrometer (CAPS) or other optical spectrometers and optical array probes provide detailed information about the horizontal and vertical distribution of aerosol and cloud properties. However, flow distortions occurring at the location where these instruments are mounted on the outside of an aircraft may directly produce artifacts in detected particle number concentration and also cause droplet deformation and/or break-up during the measurement process. Several studies have investigated flow-induced errors assuming that air is incompressible. However, for fast-flying aircraft, the impact of air compressibility is no longer negligible. In this study, we combine airborne data with numerical simulations to investigate the flow around wing-mounted instruments and the induced errors for different realistic flight conditions. A correction scheme for deriving particle number concentrations from in-situ aerosol and cloud probes is proposed, and a new formula is provided for deriving the droplet volume from images taken by optical array probes, reducing errors by up to one order of magnitude. Shape distortions of liquid droplets can either be caused by errors in the speed with which the images are recorded or by aerodynamic forces acting at the droplet surface caused by changes in the airflow around the instrument. These forces can lead to the dynamic breakup of droplets causing artifacts in particle number concentration and size. Furthermore, an estimation of the critical breakup diameter, as a function of flight conditions is provided. Experimental data show that flow speed at the instrument location is smaller than the ambient flow speed. Our simulations confirm the observed difference and reveal a size-dependent impact on particle speed and concentration. This leads, on average, to a 25 % overestimation of the number concentration of particles larger than ~10 μm} diameter and causes distorted images of droplets and ice crystals if the flow values recorded at the instrument are used. With the proposed correction scheme both errors are significantly reduced by a factor 10. Although the presented correction scheme is derived for the DLR Falcon research aircraft (SALTRACE campaign) and validated for the DLR Falcon (A-LIFE campaign) and the NASA DC-8 (ATom campaign), the general conclusions hold for any fast-flying research airplane.