Transitions to, and Correlates of, Suicidal Ideation, Plans, and Unplanned and Planned Suicide Attempts Among 3,729 Men and Women With Alcohol Dependence

Conner, Kenneth R.; Hesselbrock, Victor; Meldrum, Sean; Schuckit, Marc A.; Bucholz, Kathleen K.; Gamble, Stephanie A.; Wines, James D.; Kramer, John

doi:10.15288/jsad.2007.68.654

Cited by 84 publications

(81 citation statements)

References 31 publications

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“…To identify potential contributions of differences in measurement we differentiated SI by duration (>1 day) but associations with cannabis involvement did not vary. In contrast, we did show a difference between suicide attempts with and without a plan: cannabis involvement was related to SANP only, confirming previous studies on number of substances used (Borges et al, 2000) and alcohol dependence (Conner et al, 2007). Even though SANPs are found to be less likely to result in completed suicide (Harriss et al, 2005), suicidal attempts, in and of themselves are amongst the leading contributors to economic burden (Palmer et al, 1995) and are powerful predictors of later completed suicide (Harris and Barraclough, 1997; Suominen et al, 2004), emphasizing the need for effective prevention strategies.…”

Section: Discussionsupporting

confidence: 90%

“…Finally, as stated by the disinhibition theory, cannabis intoxication prior to an attempt could also directly lead to an increased risk of suicide attempt. Related studies (Borges et al, 2000; Conner et al, 2007) allude to the possible role of facets of disinhibited behavior as mediators. While we did not assess substance-induced disinhibition or trait level aggression in our study, the inclusion of conduct disorder (which encompasses both facets to some degree) did not attenuate the association.…”

Section: Discussionmentioning

confidence: 99%

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The relationship between cannabis involvement and suicidal thoughts and behaviors

Delforterie¹,

Lynskey²,

Huizink³

et al. 2015

Drug and Alcohol Dependence

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Background In the present study, we examined the relationship between cannabis involvement and suicidal ideation (SI), plan and attempt, differentiating the latter into planned and unplanned attempt, taking into account other substance involvement and psychopathology. Methods We used two community-based twin samples from the Australian Twin Registry, including 9,583 individuals (58.5% female, aged between 27 and 40). The Semi-Structured Assessment of the Genetics of Alcoholism (SSAGA) was used to assess cannabis involvement which was categorized into: (0) no cannabis use (reference category); (1) cannabis use only; (2) 1–2 cannabis use disorder symptoms; (3) 3 or more symptoms. Separate multinomial logistic regression analyses were conducted for SI and suicide attempt with or without a plan. Twin analyses examined the genetic overlap between cannabis involvement and SI. Results All levels of cannabis involvement were related to SI, regardless of duration (Odds ratios [ORs] = 1.28 – 2.00, p < 0.01). Cannabis use and endorsing ≥3 symptoms were associated with unplanned (SANP; ORs = 1.95 and 2.51 respectively, p < 0.05), but not planned suicide attempts (p > 0.10). Associations persisted even after controlling for other psychiatric disorders and substance involvement. Overlapping genetic (rG=0.45) and environmental (rE=0.21) were responsible for the covariance between cannabis involvement and SI. Conclusions Cannabis involvement is associated, albeit modestly, with SI and unplanned suicide attempts. Such attempts are difficult to prevent and their association with cannabis use and cannabis use disorder symptoms requires further study, including in different samples and with additional attention to confounders.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

The relationship between cannabis involvement and suicidal thoughts and behaviors

Delforterie¹,

Lynskey²,

Huizink³

et al. 2015

Drug and Alcohol Dependence

View full text Add to dashboard Cite

show abstract

“…Following the method of Conner et al (2007), an ordinal level, offspring suicidal behavior variable was created as follows: (a) nonsuicidal, (b) ideation, (c) ideation plus plan, and (d) ideation, plus plan and attempt or ideation plus attempt.…”

Section: Offspring Suicidal Behaviormentioning

confidence: 99%

Suicidal Behavior, Smoking, and Familial Vulnerability

Scherrer

Grant

Agrawal

et al. 2011

Nicotine & Tobacco Research

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“…In one study [28], approximately one half of 3729 adults with a current diagnosis of alcohol dependence had a history of suicidal ideation. In females, substance abuse was associated with increased rates of unplanned and planned suicide attempts.…”

Section: Relationship To Suicidementioning

confidence: 99%

Gender differences in adolescent substance abuse

Kloos

Weller²,

Chan³

et al. 2009

Curr Psychiatry Rep

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Gender differences in the epidemiology, comorbidities, and treatment responses of substance abuse have been described in adults. However, a growing body of data suggests that gender differences also exist in adolescents with substance abuse. Unfortunately, research is still limited in this age group. This article reviews gender differences in the diagnosis, presentation, course of illness, and treatment response of substance abuse in adults and adolescents. Adolescent substance abuse treatments that take into account these gender differences are also discussed.

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Transitions to, and Correlates of, Suicidal Ideation, Plans, and Unplanned and Planned Suicide Attempts Among 3,729 Men and Women With Alcohol Dependence

Cited by 84 publications

References 31 publications

The relationship between cannabis involvement and suicidal thoughts and behaviors

The relationship between cannabis involvement and suicidal thoughts and behaviors

Suicidal Behavior, Smoking, and Familial Vulnerability

Gender differences in adolescent substance abuse

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