Transitorische akantholytische Dermatose (M. Grover)

Streit, Markus; Be, Paredes; Lr, Braathen; Cu, Brand

doi:10.1007/s001050051112

Cited by 6 publications

(1 citation statement)

References 11 publications

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“…Bei ersterem sind die Läsionen klassischerweise vorübergehend und histologisch findet sich keine Invagination des Stratum corneum [18] und wenig dyskeratotische Zellen [18], der Stamm ist am häufigsten befallen [15]. Bei ersterem sind die Läsionen klassischerweise vorübergehend und histologisch findet sich keine Invagination des Stratum corneum [18] und wenig dyskeratotische Zellen [18], der Stamm ist am häufigsten befallen [15].…”

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Papulöse akantholytische Dyskeratose

et al. 2001

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Papular acantholytic dyskeratosis is a very rare skin disease, which shows a suprabasilar cleft with acantholytic and dyskeratotic cells, simulating the light microscopic picture of Darier disease. In this condition, the lesions are acquired without a genetic basis. We observed a 40-year-old woman with about 200 papules on the lower aspects of her legs; histological examination showed changes similar to Darier disease. Transmission electron microscopy showed a reduced number of desmosomes and perinuclear distribution of tonofilaments. The lesions were successfully treated with cryotherapy with spray technique.

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Section: Diskussionunclassified

Papulöse akantholytische Dyskeratose

et al. 2001

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Enfermedad de Grover en varón africano

Martín¹,

Paz²,

Ferrer³

et al. 2014

Piel

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A Rare Case of Transient Acantholytic Dermatosis (AKA. Grover’s Disease) with Concomitant Pediculosis Pubis: An Atypical Presentation and First Documented Case Report

et al. 2021

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A 66-year-old male presented with a one-month history of persistent pruritic eruptions distributed mainly on the trunk. A punch biopsy from the left upper abdomen revealed focal acantholytic dyskeratosis with mixed inflammatory infiltrate in the dermis composed of numerous eosinophils. Grover’s disease was diagnosed based on the clinical and histopathological findings. Appropriate treatment was initiated but failed to relieve symptoms of itchiness. A further investigation of the hair follicles under mineral oil preparation revealed an infestation of pediculosis pubis. Subsequent treatment with Ivermectin and permethrin cream led to the complete resolution of his symptoms. This case report highlights an unusual and first documented case of Grover’s disease with a concomitant infestation of pediculosis pubis. To date, no reported cases in the literature have associated Grover’s disease with pubic lice infestation. However, there are three reported cases of concurrent scabies and Grover’s disease in the literature. This rare case underscores the clinical value in further investigating treatable underlying conditions in patients with suspected transient acantholytic dermatosis.

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Transitorische akantholytische Dermatose (M. Grover)

Abstract: Our 21 cases reflect in general the literature. Nevertheless, the long persistence of the skin lesions was striking perhaps making the term transient somewhat inaccurate.

Cited by 6 publications

References 11 publications

Papulöse akantholytische Dyskeratose

Papulöse akantholytische Dyskeratose

Enfermedad de Grover en varón africano

A Rare Case of Transient Acantholytic Dermatosis (AKA. Grover’s Disease) with Concomitant Pediculosis Pubis: An Atypical Presentation and First Documented Case Report

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