[Translated article] BIOBADATOP Spanish Atopic Dermatitis Registry: Description and Early Findings

Munera‐Campos, Mónica; Chicharro, Pablo; Quesada, A González; Menendez, A. Florez; Dovao, P de la Cueva; Arnau, A.M. Giménez; Calzada, Yolanda Gilaberte; Serna, Mercedes Rodríguez; Montero, T; Salvador, Juan Francisco Silvestre; González, M Elosua; Alcázar, E. del; Santamaría, Carlos; Sánchez‐Pérez, Javier; Hernández, G. Carretero; Oh, H Jin Suh; Fernández, C.; Curto‐Barredo, Laia; Bertolín, M.; Bielsa, Alba Navarro; Ruiz, A Ballano; Estrada, Rafael Botella; Santiago, Salvador Arias; Betlloch, Isabel; Gullón, Gastón Roustán; Dı́az, Abel; Descalzo, MA; García‐Doval, I.; Carrascosa, J.M.

doi:10.1016/j.ad.2023.05.010

Cited by 3 publications

(1 citation statement)

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“…Applying "omics" methodology to the entire SoDE might result in a rearrangement of the diseases into more coherent entities diagnosed reliably via validated molecular and clinical criteria. The ambitious goal of collecting "omics" results sufficient to elaborate better diagnostic criteria and systematize the entire SoDE in its diversity would require a harmonized collaboration of dermatology and allergy societies, departments and research centers in many countries and continents, expanding the concept and scope of already existing registries devoted to AD [150,151]. Such action would ultimately enable a more accurate diagnosis, resulting in more effective disease management and better quality of life for patients.…”

Section: Future Directionsmentioning

confidence: 99%

Diseases from the Spectrum of Dermatitis and Eczema: Can “Omics” Sciences Help with Better Systematics and More Accurate Differential Diagnosis?

Śpiewak

2023

IJMS

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Researchers active in the field of inflammatory skin diseases from the spectrum of dermatitis and eczema are well aware of a considerable overlap in the clinical pictures and proposed sets of diagnostic criteria for these diseases, which can hardly be overcome through the clinical or epidemiological research. In effect, patients are included in studies based on vague and overlapping criteria, while heterogeneous study populations may, in turn, lead to non-representative outcomes and continued confusion. In this narrative review, a systematics of diseases from the spectrum of dermatitis and eczema is proposed based on the origins of causative factors and the pathomechanisms involved. Difficulties in differentiating between these diseases are discussed, and the extent to which advances in the “omics” sciences might help to overcome them is considered. Of all the “omics” research in this field, more than 90% of the published papers were devoted to atopic dermatitis, with a striking underrepresentation of other diseases from the spectrum of dermatitis and eczema, conditions which collectively exceed the rates of atopic dermatitis by far. A greater “omics” research effort is urgently needed to tackle other dermatitides, like allergic, irritant and protein contact dermatitis, as well as radiation, seborrheic, stasis or autoimmune dermatitis. Atopic dermatitis findings should be validated not only against healthy donors but also other dermatitides. A clinic-oriented approach is proposed for future “omics” studies in the field of dermatitis and eczema.

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Section: Future Directionsmentioning

confidence: 99%