[Translated article] Characteristics of Acral Lentiginous Melanoma According to Location in Stress- or Non–Stress-Bearing Areas: A Retrospective Study of 95 Patients

Abisaad, Juanita Arango; Grisales, Valeria Arciniegas; García, Á. Londoño; Trespalacios, Elsa María Vásquez; Calfat, Guillermo Jiménez; López, J.M. Cuello

doi:10.1016/j.ad.2021.08.012

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…[3][4][5][6] Compared with White patients, dark-skinned individuals more commonly acquire melanoma on acral areas, such as the hands and feet. [7][8][9] Especially, acral melanoma occurs most commonly on weight-bearing areas of the sole, [10][11][12][13] which recent research has attributed to nuclear membrane damage resulting from mechanical stress. 14 Surgical excision of tumors at such sites results in significant distress for patients, as weight-bearing and walking are impaired.…”

Section: Introductionmentioning

confidence: 99%

Comparison of full‐thickness skin graft and punch grafting in the reconstruction of plantar defects

Lee,

Nam,

et al. 2023

The Journal of Dermatology

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Acral melanoma commonly occurs on weight‐bearing areas of the sole. Reconstruction of such areas presents a surgical challenge due to limited availability and mobility of local skin. Thus, we aimed to compare the scar outcome of full‐thickness skin graft (FTSG) and punch grafting in the reconstruction of plantar defects after melanoma surgery. We retrospectively reviewed six patients who underwent both FTSG for nonweight‐bearing areas and punch grafting for weight‐bearing areas. We compared results of FTSG and punch grafting within the same patient. Photos of completely healed scars were graded using the Stony Brook Scar Evaluation Scale (SBSES). The averages of the FTSG scores and the punch graft scores, as measured by the SBSES, were statistically compared. Punch grafting yielded a better outcome than FTSG, according to the SBSES. The average of the punch grafting scars was 4.67, which was significantly greater (p = 0.004) than that of FTSG scar scores at 1.83. For weight‐bearing areas, punch grafting should be considered as the first option of reconstruction, with FTSG as a second option for nonweight‐bearing areas. Overall, this combined approach provides an effective and safe method for reconstruction of extensive plantar wounds.

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Section: Introductionmentioning

confidence: 99%

Comparison of full‐thickness skin graft and punch grafting in the reconstruction of plantar defects

Lee,

Nam,

et al. 2023

The Journal of Dermatology

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Anatomic mapping of acral melanocytic nevi and acral lentiginous melanomas among Taiwanese patients: A retrospective cohort study

Chen,

Lin,

Liao

et al. 2024

Journal of the Formosan Medical Association

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Early-stage acral melanoma with a history of trauma associated with a poor prognosis:A multicenter data analysis of 468 cases

滕,

Wu,

Cai

et al. 2024

Preprint

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Background：Previous studies have suggested that trauma may be a risk factor for the development and prognosis of acral melanoma (AM), but the available evidence is limited.This study aimed to explore the impact of trauma on AM recurrence and survival. Methods：This population-based retrospective cohort study included patients with acral melanoma with a clear history of trauma who were treated at five melanoma treatment centers in China from 2009 to 2023. Data were analyzed July 2023 to August 2023. Baseline characteristics of the two groups were analyzed using the chi-square test. Disease-free survival (DFS) and overall survival (OS) were analyzed using the Kaplan-Meier method. Factors associated with recurrence and survival were determined using univariate and multivariate Cox regression analysis. Results：A total of 468 AM patients were included in this study, with 101 in the trauma group and 367 in the non-trauma group. In the overall population, the median follow-up time was 57.4 months (95%CI, 53.84-61.03), with 248 (53.0%) males and 220 (47.0%) females. The peak age of onset was between 60-69 years old (31.2%) . In the trauma group, the plantars area was the most frequently affected site (54.5%), followed by the hallux toe (17.8%) and thumb (9.9%). The proportion of patients with ulcer (P=0.027) , mitosis rate ≥1 (P=0.036), and Clark level IV-V (P=0.009) was significantly higher in the trauma group compared to the non-trauma group. Multivariate analysis demonstrated that trauma was an independent risk factor for both DFS and OS in stage I-II. Furthermore, the cumulative survival rate revealed that the I-II trauma group had significantly lower than the non-trauma group. Conclusions：The results of this cohort study showed that trauma was found to be an independent risk factor for DFS in AM patients with stage I-II, affecting DFS and OS in AM.

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[Translated article] Characteristics of Acral Lentiginous Melanoma According to Location in Stress- or Non–Stress-Bearing Areas: A Retrospective Study of 95 Patients

Cited by 3 publications

References 24 publications

Comparison of full‐thickness skin graft and punch grafting in the reconstruction of plantar defects

Comparison of full‐thickness skin graft and punch grafting in the reconstruction of plantar defects

Anatomic mapping of acral melanocytic nevi and acral lentiginous melanomas among Taiwanese patients: A retrospective cohort study

Early-stage acral melanoma with a history of trauma associated with a poor prognosis:A multicenter data analysis of 468 cases

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