[Translated article] Lipoatrophia semicircularis: Clinical study and follow-up of 76 cases in Madrid, Spain. Classification proposal

Bru-Gorraiz, Francisco-Javier; Comunión-Artieda, A.; Bordel-Nieto, I.; Martín-Gorgojo, Alejandro

doi:10.1016/j.ad.2021.05.022

Actas Dermo-Sifiliográficas

2022

DOI: 10.1016/j.ad.2021.05.022

|View full text |Cite

[Translated article] Lipoatrophia semicircularis: Clinical study and follow-up of 76 cases in Madrid, Spain. Classification proposal

Francisco-Javier Bru-Gorraiz

A. Comunión-Artieda

I. Bordel-Nieto

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

An Experimental Murine Model to Study Lipoatrophia Semicircularis

Palomar-Gallego,

Ramiro-Bargueño,

Cuerda-Galindo

et al. 2024

CIMB

View full text Add to dashboard Cite

Lipoatrophia semicircularis is a benign pathology characterized by subcutaneous tissue atrophy that affects the skin and related structures. Its etiology remains unclear; however, in the recent few years, it has been proposed that electrostatic charges could be a potential factor. Based on this hypothesis, the aim of this work is to study the cause–effect relation between electrostatic energy and LS, providing insights into the molecular mechanisms. For this purpose, an experimental murine model was created using obese mice. One group served as a control and the other groups involved charging clothes with varying connections to the ground: through the skin, through the clothes or not connected to the ground). Skin biopsies showed that the most significant lesions, including lipophagic granulomas with inflammatory infiltrate, were found in the first group (connected to the ground through the skin). Lipophagic reactions without an inflammatory infiltrate were observed in the other groups subjected to electrical discharges. In the control mice, no histological changes were observed. Oxidative processes were also measured in lower limbs tissue. Malondialdehyde levels significantly increased in the lower limbs after electrostatic discharges. However, the presence of ground through a wire attached to highly conductive clothes around the thigh significantly reduced the effect of electrostatic charges on lipid peroxidation. To our knowledge, this is the first study in which an experimental model has been used to reproduce LS induced by electrostatic energy, suggesting a cause–effect relationship between electrostatic charge and discharge with fat tissue lesion.

show abstract

An Experimental Murine Model to Study Lipoatrophia Semicircularis

Palomar-Gallego,

Ramiro-Bargueño,

Cuerda-Galindo

et al. 2024

CIMB

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

[Translated article] Lipoatrophia semicircularis: Clinical study and follow-up of 76 cases in Madrid, Spain. Classification proposal

Cited by 1 publication

References 15 publications

An Experimental Murine Model to Study Lipoatrophia Semicircularis

An Experimental Murine Model to Study Lipoatrophia Semicircularis

Contact Info

Product

Resources

About