Translation and validation of the arabic version of the myasthenia gravis activities of daily living scale

Abstract

Introduction We translated the myasthenia gravis (MG)‐specific activities of daily living (MG‐ADL) scale into Arabic (MG‐ADL‐A) and assessed its psychometric properties. Methods We assessed reliability using Cronbach's α, reproducibility using the intraclass correlation coefficient, and validity using Spearman's correlations with MG composite (MGC) score, MG‐specific manual muscle test (MG‐MMT), and MG quality‐of‐life revised Arabic version (MGQOL15R‐A). Differences in MG‐ADL‐A scores among patients with different disease severity were evaluated by using the Kruskal–Wallis test. Sensitivity to change was examined by using the Wilcoxon signed‐rank test. Results We recruited 87 patients. The mean MG‐ADL‐A score was 3.38 ± 3.38 (α = 0.77, ICC = 0.99). The correlation coefficients between the MG‐ADL‐A and MGQOL15R‐A, MGC, and MG‐MMT were 0.63, 0.74, and 0.61, respectively (P < 0.001). The MG‐ADL‐A discriminated between different severity groups and was responsive to clinical improvement at follow‐up. Discussion The MG‐ADL‐A has rigorous psychometric properties and can be used with Arabic‐speaking patients with MG. Muscle Nerve 59:583–583, 2019

Reliability and Validity of Turkish Myasthenia Gravis-Activities of Daily Living Scale

“…Raggi et al (2017) also reported that MG-ADL and MGC results were well correlated. Alanazy et al (2019) found a similar result as well. These results were expected, as MGC and MG-ADL share common evaluation parameters.…”

“…Test–retest reliability was excellent with an ICC of .96, indicating the reproducibility of MG-ADL-T. Test–retest results have also been found to be excellent in other languages (Alanazy et al, 2019; Lee et al, 2017; Raggi et al, 2017; Rozmilowska et al, 2018). The test–retest correlation of the MG-ADL-T was very high for all the items, similar to the original article, which reported a test–retest reliability of about 93.7% (Mukaka, 2012; Muppidi et al, 2011).…”

“…It has even been suggested not to use Cronbach’s alpha if the scale is suspected of being multifaceted (Streiner, 2003). However, Cronbach’s alpha has previously been used in the validity and reliability studies of MG-ADL in different languages and the value was .77 in Italian and Arabic versions (Alanazy et al, 2019; Raggi et al, 2017). In our study, we found Cronbach’s alpha, which is the criterion used for internal consistency, to be .67.…”

“…The MG-ADL has been the most widely used patient-reported scale as there is no other scale for assessing ADL. The scale, originally in English, is available in Polish, Italian, Arabic, and Korean translations (Alanazy et al, 2019; Lee et al, 2017; Raggi et al, 2017; Rozmilowska et al, 2018). Although the number of clinical trials is increasing in MG Turkish population (Salci et al, 2018; Tascilar et al, 2017; Yildiz Celik et al, 2019), the Turkish version of MG-ADL has not been yet prepared.…”

Clinical features and outcomes of patients with myasthenia gravis

“…However, given the fluctuating nature of MG and because the MG-specific outcome measures were derived from the last follow-up visit, one should acknowledge that the good outcomes reported here do not reflect long-term stability of the disease in our cohort. However, most of the patients in this study had previously participated in the study validating the Arabic versions of the MG-QOL15R and MG-ADL, 10,11 which involved collecting MG-specific outcome measure data at different times than data collected for this study. As these studies also report milder disease symptoms among the patients )MG-QOL15R-A: 84.6%; MG-ADL-A: 89.7%(, we can consider that the overall prognosis of patients in our cohort is good.…”