Translation of biomaterials from bench to clinic

Evidence-based biomaterials research

“…The development processes of products executed by companies (the right side of the dotted line in Fig. 2 ) need to follow the practice regulated by regulatory authorities [ 5 ]. Without getting the details of design control processes for the development of biomaterial products, the development process of biomaterials products can be categorized as stages of non-clinical and clinical evaluations.…”

Advancing medical device regulatory reforms for innovation, translation and industry development in China

“…All medical devices must fulfill clinical needs and solve practical problems [ [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] ]. The academic value of research findings is not always aligned with their clinical values.…”

“…The academic value of research findings is not always aligned with their clinical values. However, if an innovation is expected to bring new technologies and products to the market, then research on market and clinical demands should be conducted as early as possible [ [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] ]. The urgent clinical needs and unsolved problems should be pinpointed to refine the research program accordingly.…”

“…The urgent clinical needs and unsolved problems should be pinpointed to refine the research program accordingly. Otherwise, it might be difficult for significant research findings to be translated into successful medical products [ [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] ].…”

Bioactive Inorganic Materials for Dental Applications: A Narrative Review

“…The release of ions from the bioactive materials elicited an effect and increased the chances of regeneration and remineralization. Various studies have been conducted to assess the bioactive potential of biomaterials in the oral environment and evaluated their performances in multiple clinical applications [ 25 , 26 , 27 , 28 ]. The outcomes of these studies showed that the bioactive materials’ applications to enhance oral health were developing at a rapid pace.…”