Transmissão vertical do HIV, da sífilis e da hepatite B no município de maior incidência de AIDS no Brasil: um estudo populacional no período de 2002 a 2007

Kupek, Emil; Oliveira, Juliana Fernandes de

doi:10.1590/s1415-790x2012000300004

Cited by 31 publications

(33 citation statements)

References 14 publications

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“…In Brazil, transmission rates remain very high and it seems unlikely to achieve the goal of global elimination of the disease (4) . In our study, it was identified an incidence rate (39.4‰) much higher than the target set to us and higher than in other national studies (13)(14)(15)(16)(17)(18)(19)(20) with the same CS criteria (21) . It is worth noting that there were diverse methodology studies, with primary data, as well as data from SI-NAN, population and hospitals.…”

Section: Discussioncontrasting

confidence: 58%

“…We have identified a considerable portion of the population studied (36.3%) that even performing appropriate prenatal visits failed to prevent the unwanted outcome. This proves the quality deficiency of prenatal care, which has been one of the main factors for the high rates of congenital syphilis, confirmed in many national studies (15)(16)(17)(18)(19)(20) . In general neonates infected by Treponema are asymptomatic at birth, a result observed in our study.…”

Section: Discussionmentioning

confidence: 52%

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IncIdence of congenItal SyphIlIS In a MetropolItan regIon of rIo de JaneIro State: SocIal InequalItIeS

Fonseca¹,

Oliveira²,

Almeida³

et al. 2013

J bra doenças sex transm

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Introduction: congenital syphilis remains a public health matter, with no perspective of reaching governmental reduction goals. There are few studies about social inequalities and its relation with this disease in Brazil. Objective: describe occurrence of congenital syphilis in a reference hospital in a Metropolitan Region of Rio de Janeiro State, according to socioeconomic and clinical-laboratorial variables as well. Methods: cross-sectional study, based on interviews, review of medical records and prenatal cards. Population: all women admitted to a maternity ward during a trimester in 2011. Maternal variables: age, schooling, skin color, income, prenatal visits. Fetus/neonate variables: birth weight, gestational age, clinical and laboratory outcomes. Incidence of congenital syphilis (Brazilian Ministry of Health criteria) was calculated for all live births and for each social and economical variable. Results: there were 666 eligible women, comprehending 576 deliveries -558 live births and 18 stillbirths. We identified 22 CS cases: 18 live births, three fetal deaths and 1 abortion. One of the neonates died in the third day of life. The incidence of CS was of 39.4/1,000 live births. Socioeconomic variableslow education, low income and black skin -were related to a greater incidence. Only 13 out of 22 cases were identified in prenatal care. Conclusion: our results pointed to social inequalities in the congenital syphilis incidence. As prenatal care is also related to socioeconomic variables, investments in quality of maternal assistance should be directed to more vulnerable women.

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Section: Discussioncontrasting

confidence: 58%

Section: Discussionmentioning

confidence: 52%

IncIdence of congenItal SyphIlIS In a MetropolItan regIon of rIo de JaneIro State: SocIal InequalItIeS

Fonseca¹,

Oliveira²,

Almeida³

et al. 2013

J bra doenças sex transm

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“…The independent variables included gender (male or female), age (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35), 36-45 and 46-65 years), education level (complete or incomplete primary or secondary school), residence region (from the seven major geographical regions of the state: Florianópolis, Extremo Oeste, Meio Oeste, Planalto Norte, Sul, Vale do Itajaí and Planalto Serrano) and previous blood donation status (never, within previous 12 months or more than 12 months ago). This model allowed for an estimation of the syphilis infection probability among those donors who did not return for follow-up testing, despite a reactive screening test result.…”

Section: Methodsmentioning

confidence: 99%

Syphilis seroprevalence estimates of Santa Catarina blood donors in 2010

Baião

Kupek

Petry³

2014

Rev. Soc. Bras. Med. Trop.

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Introduction: Knowledge of blood donor characteristics is essential to better guide clinical and serological screening for hemotherapy. The objective of this study was to determine the syphilis seroprevalence and the associated factors of blood donors in the State of Santa Catarina, Brazil. Methods: This population-based study from the State of Santa Catarina used information obtained from blood donation records. We analyzed 83,396 blood donor records generated from donors who were considered eligible to donate between January and August 2010. The aim of the study was to estimate the syphilis seroprevalence and its relationship with educational level, age, gender, geographical region and having donated blood in the past 12 months. We used descriptive analyses and a Poisson regression to calculate the prevalence ratios for the variables of interest. Results: We found a 0.14% overall seroprevalence and signifi cant differences among the following: fi rst-time blood donors (0.19%) versus repeat donors (0.03% to 0.08%); low educational levels (0.30%) versus medium and high educational levels (0.08% to 0.19%); and donors who did not report their residence (0.88%) or age (6.94%) versus those who did. Increased syphilis seroprevalence was also signifi cantly associated with increased age. Conclusion: High syphilis seroprevalence was associated with lower educational level, age, fi rst-time donation and the failure to provide age or residence information.

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“…Kupeck (2001) estimated the risk of HBsAg transmission by studying historical blood donor series in the State of Santa Catarina in the 1990s (109) and concluded that despite reduced risk, the incidence density would be three infections per 1,000 person-years. More recently, Silva et al (121) analyzed notifi cations to the Information System for Notifi able Diseases and estimated that the incidence in 2009 in Brazil and Santa Catarina was 11.5 and 17 infections per 100,000 inhabitants, respectively (121) .…”

Section: Incidence Datamentioning

confidence: 99%

Distribution of hepatitis B infection in Brazil: the epidemiological situation at the beginning of the 21 st century

Souto

2015

Rev. Soc. Bras. Med. Trop.

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Brazil was formerly considered a country with intermediate hepatitis B endemicity, with large heterogeneity between Brazilian regions and areas of high prevalence, especially in the Amazon basin. Systematic vaccination of children was initiated in 1998. Between 2004 and, a large population-based study reported decreased prevalence in all regions of Brazil. This review analyzed the current hepatitis B epidemiological situation in Brazil through a systematic search of the scientifi c literature in MEDLINE, LILACS, and CAPES thesis database, as well as disease notifi cations to the Information System for Notifi able Diseases. The search strategy identifi ed 87 articles and 13 theses, resulting in 100 total publications. The most recent results indicate reduced hepatitis B prevalence nationwide, classifying Brazil as having low endemicity. Most studies showed HBV carrier prevalence less than 1%. However, there are still isolated regions with increased prevalence, particularly the Amazon, as well as specifi c groups, such as homeless people in large cities and isolated Afro-descendant communities in the center of the country. This review alsao detected successful vaccination coverage reported in a few studies around the country. The prevalence of anti-HBs alone ranged from 50% to 90%. However, isolated and distant localities still have low coverage rates. This review reinforces the downward trend of hepatitis B prevalence in Brazil and the need to intensify vaccination strategies for young people and adults in specifi c regions with persisting higher HBV infection prevalence.

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Transmissão vertical do HIV, da sífilis e da hepatite B no município de maior incidência de AIDS no Brasil: um estudo populacional no período de 2002 a 2007

Cited by 31 publications

References 14 publications

IncIdence of congenItal SyphIlIS In a MetropolItan regIon of rIo de JaneIro State: SocIal InequalItIeS

IncIdence of congenItal SyphIlIS In a MetropolItan regIon of rIo de JaneIro State: SocIal InequalItIeS

Syphilis seroprevalence estimates of Santa Catarina blood donors in 2010

Distribution of hepatitis B infection in Brazil: the epidemiological situation at the beginning of the 21 st century

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