Transmission dynamics of dengue in Costa Rica: the role of hospitalizations

Abstract

For decades, dengue virus has caused major problems for public health officials in tropical and subtropical countries around the world. We construct a compartmental model that includes the role of hospitalized individuals in the transmission dynamics of dengue in Costa Rica. The basic reproductive number, R0, is computed, as well as a sensitivity analysis on R0 parameters. The global stability of the disease-free equilibrium is established. Numerical simulations under specific parameter scenarios are performed to determine optimal prevention/control strategies.

Potential application of chitosan stabilized silver nanoparticles for simultaneous control of dengue virus and mosquito vectors

“…The virus usually infects humans through the bites of infected female mosquitoes. After an incubation period of 3-10 d, the patient has some symptoms: fever, headache, muscle, and joint pains, nausea, and skin rash [2].…”