2023
DOI: 10.1002/mma.9256
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Transmission dynamics of visceral leishmaniasis with PKDL and periodic delays

Abstract: We consider the transmission of visceral leishmaniasis in three populations: humans, dogs and sandflies. To investigate the effects of spatial heterogeneity and temporal periodicity on disease transmission, a nonlocal periodic reaction-diffusion equation model is developed. We introduce the basic reproduction number R 0 and establish the global dynamics. Numerical simulations show that (i) R 0 is overestimated in the absence of spatial heterogeneity; (ii) R 0 is underestimated without considering the effect of… Show more

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“…Intensive studies over the years revealed that mathematical modeling and simulation can play a significant role in understanding the reasons for diverse infectious diseases, thereby predicting the possible cure. It is needless to say that mathematical modeling of VL has a rich history wherein numerous reports exist on the classical, fractional, statistical, machine learning models, and so forth [1–9]. In addition, it was acknowledged that the fractional calculus can offer deep insights into the dynamics of VL, leading to more accurate model and effective treatment strategies.…”
Section: Introductionmentioning
confidence: 99%
“…Intensive studies over the years revealed that mathematical modeling and simulation can play a significant role in understanding the reasons for diverse infectious diseases, thereby predicting the possible cure. It is needless to say that mathematical modeling of VL has a rich history wherein numerous reports exist on the classical, fractional, statistical, machine learning models, and so forth [1–9]. In addition, it was acknowledged that the fractional calculus can offer deep insights into the dynamics of VL, leading to more accurate model and effective treatment strategies.…”
Section: Introductionmentioning
confidence: 99%