Transmission Electron Microscopy Used to Diagnose Acute Toxoplasmosis in a Quarantined, Captive Born Cynomolgus Macaque

Megill, John; MacGuire, Jamus; Jackson, Rebel; Janovitz, Evan B.; Dubey, J. P.

doi:10.1017/s1431927614008770

Cited by 1 publication

(1 citation statement)

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“…Protozoal infections encountered in macaques include Cryptosporidium parvum, Enterocytozoon bieneusi, Plasmodium spp., Trichomonas spp., Acanthamoeba spp., Toxoplasma gondii 27 and Trypanosoma cruzi 28 . Toxoplasma gondii systemic infection can be seen spontaneously in macaques 29 and is characterized by necrosis and inflammation in the brain, lungs, mesenteric lymph node, liver and/or heart. Trypanosoma cruzi infection can be the cause of inflammation in the heart and/or brain of cynomolgus monkeys.…”

Section: Parasite/parasitic Granuloma: Multiple Tissuesmentioning

confidence: 99%

International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Non-proliferative and Proliferative Lesions of the Non-human Primate (<i>M. fascicularis</i>)

et al. 2021

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The INHAND (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions Project (www.toxpath.org/inhand.asp) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying microscopic lesions observed in most tissues and organs from the nonhuman primate used in nonclinical safety studies. Some of the lesions are illustrated by color photomicrographs. The standardized nomenclature presented in this document is also available electronically on the internet (http://www.goreni.org/). Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous lesions as well as lesions induced by exposure to test materials. Relevant infectious and parasitic lesions are included as well. A widely accepted and utilized international harmonization of nomenclature for lesions in laboratory animals will provide a common language among regulatory and scientific research organizations in different countries and increase and enrich international exchanges of information among toxicologists and pathologists.

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Section: Parasite/parasitic Granuloma: Multiple Tissuesmentioning

confidence: 99%