Transmission of methicillin-resistant staphylococcus aureus in the long term care facilities in Hong Kong

Cheng, Vincent Chi-Chung; Tai, Josepha W.M.; Wong, Zoie Shui-Yee; Chen, Jonathan Hon-Kwan; Pan, Kris B Q; Hai, Yizchen; Ng, Wing-Chun; Chow, Denise M K; Yau, Miranda Chong-Yee; Chan, Jasper Fuk‐Woo; Wong, Sally Cheuk-Ying; Tse, Herman; Chan, Sophia; Tsui, Kwok Leung; Chan, Felix Hon-Wai; Ho, Pak‐Leung; Yuen, Kwok‐Yung

doi:10.1186/1471-2334-13-205

Cited by 47 publications

(52 citation statements)

References 42 publications

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“…The MRSA prevalence we observed was lower than in MRSA surveys in recent years in the US [41][42][43][44][45], China [46], the UK [16], France [20], Ireland [15], and Italy [24], but higher than in the Netherlands and Sweden [14,22] (Table 3). …”

Section: Discussioncontrasting

confidence: 66%

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Hogardt

Proba

Mischler³

et al. 2015

Eurosurveillance

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Multidrug-resistant organisms (MDRO) and in particular multidrug-resistant Gram-negative organisms (MRGN) are an increasing problem in hospital care. However, data on the current prevalence of MDRO in long-term care facilities (LTCFs) are rare. To assess carriage rates of MDRO in LTCF residents in the German Rhine-Main region, we performed a point prevalence survey in 2013. Swabs from nose, throat and perineum were analysed for meticillin-resistant Staphylococcus aureus (MRSA), perianal swabs were analysed for extended-spectrum beta-lactamase (ESBL)-producing organisms, MRGN and vancomycin-resistant enterococci (VRE). In 26 LTCFs, 690 residents were enrolled for analysis of MRSA colonisation and 455 for analysis of rectal carriage of ESBL/MRGN and VRE. Prevalences for MRSA, ESBL/MRGN and VRE were 6.5%, 17.8%, and 0.4%, respectively. MRSA carriage was significantly associated with MRSA history, the presence of urinary catheters, percutaneous endoscopic gastrostomy tubes and previous antibiotic therapy, whereas ESBL/ MRGN carriage was exclusively associated with urinary catheters. In conclusion, this study revealed no increase in MRSA prevalence in LTCFs since 2007. In contrast, the rate of ESBL/MRGN carriage in German LTCFs was remarkably high. In nearly all positive residents, MDRO carriage had not been known before, indicating a lack of screening efforts and/or a lack of information on hospital discharge.

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Section: Discussioncontrasting

confidence: 66%

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Hogardt

Proba

Mischler³

et al. 2015

Eurosurveillance

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“…used molecular typing to show a high similarity between MRSA strains isolated from surveillance cultures and clinical cultures collected from patients on dialysis treatment [30]. And a study conducted at long-term care facilities in Hong Kong reported a significant dissemination of MRSA, reinforcing the need to adopt measures to reduce the transmission of this microorganism [36]. …”

Section: Discussionmentioning

confidence: 99%

Risk factors for bloodstream infection in patients at a Brazilian hemodialysis center: a case–control study

et al. 2015

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BackgroundInfection is the leading cause of morbidity and the second leading cause of mortality in patients on renal replacement therapy. The rates of bloodstream infection in hemodialysis patients vary according to the type of venous access used. Gram-positive bacteria are most frequently isolated in blood cultures of hemodialysis patients. This study evaluated risk factors for the development of bloodstream infections in patients undergoing hemodialysis.MethodsRisk factors associated with bloodstream infections in patients on hemodialysis were investigated using a case–control study conducted between January 2010 and June 2013. Chronic renal disease patients on hemodialysis who presented with positive blood cultures during the study were considered as cases. Controls were hemodialysis patients from the same institution who did not present with positive blood cultures during the study period. Data were collected from medical records. Logistic regression was used for statistical analysis.ResultsThere were 162 patients included in the study (81 cases and 81 controls). Gram-positive bacteria were isolated with the highest frequency (72%). In initial logistic regression analysis, variables were hypertension, peritoneal dialysis with previous treatment, type and time of current venous access, type of previous venous access, previous use of antimicrobials, and previous hospitalization related to bloodstream infections. Multiple regression analysis showed that the patients who had a central venous catheter had an 11.2-fold (CI 95%: 5.17–24.29) increased chance of developing bloodstream infections compared with patients who had an arteriovenous fistula for vascular access. Previous hospitalization increased the chance of developing bloodstream infections 6.6-fold (CI 95%: 1.9–23.09).ConclusionsInfection prevention measures for bloodstream infections related to central venous catheter use should be intensified, as well as judicious use of this route for vascular access for hemodialysis. Reducing exposure to the hospital environment through admission could contribute to a reduction in bloodstream infections in this population.

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“…Furthermore, intravenous vancomycin is now administered for prophylaxis instead of cefazolin. 26 There are many potential risk factors for PJI documented in the literature. Nonetheless, only a limited number were included in this study, most of which are not be modifiable.…”

Section: Risk Factor Onset Of Infectionmentioning

confidence: 99%

Bacteriology and risk factors associated with periprosthetic joint infection after primary total knee arthroplasty: retrospective study of 2543 cases

Siu

Ng²,

Chan

et al. 2018

Hong Kong Med J

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Transmission of methicillin-resistant staphylococcus aureus in the long term care facilities in Hong Kong

Cited by 47 publications

References 42 publications

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Risk factors for bloodstream infection in patients at a Brazilian hemodialysis center: a case–control study

Bacteriology and risk factors associated with periprosthetic joint infection after primary total knee arthroplasty: retrospective study of 2543 cases

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