Transmission of multiple antimicrobial-resistant Staphylococcus intermedius between dogs affected by deep pyoderma and their owners

Guardabassi, Luca; Loeber, M.E; Jacobson, Astrid R.

doi:10.1016/j.vetmic.2003.09.021

Cited by 186 publications

(164 citation statements)

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“…Reported rates of canine carriage vary widely, but higher levels reported in early studies may be due to the inability to distinguish between S. aureus and S. intermedius, the staphylococcal species most frequently isolated from dogs [15,16]. Although <10 % of dogs may carry S. aureus [15], canine infections with MRSA have been reported [17,18].…”

Section: Introductionmentioning

confidence: 99%

Prevalence ofStaphylococcus aureuscarriage among dogs and their owners

2007

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SUMMARYCase reports have indicated transmission of Staphylococcus aureus between humans and pets. We investigated associations between level of contact between dog and owner, and S. aureus colonization. In a cross-sectional study, nasal carriage and antibiotic susceptibility of S. aureus was determined for 830 dogs and 736 owners. Relatedness of isolates was investigated using antibiograms and pulsed-field gel electrophoresis (PFGE). Associations between carriage and demographics or amount of contact between owners and dogs were documented. S. aureus was isolated in 24% of humans and 8 . 8% of dogs. Antibiotic resistance was significantly more common in canine isolates. Of 17 owner/dog colonized pairs, six were indistinguishable by PFGE. Colonization of dogs was not associated with close human contact, but was strongly associated with health-care occupations (OR 3 . 29, P=0 . 002). In outbreak situations health-care workers' pets should be considered as a source of S. aureus. High rates of resistance indicate increased monitoring of antibiotic use in veterinary practice is needed.

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Section: Introductionmentioning

confidence: 99%

Prevalence ofStaphylococcus aureuscarriage among dogs and their owners

2007

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“…Beside this, S. pseudintermedius could be transferred from infected and/ or colonized pets to humans, which causes an increasing public health concern [1] . Staphylococcus pseudintermedius is occasionally isolated from serious human infections, particularly from people who are in close contact with pets, such as small animal veterinarians and pet owners [2][3][4][5] .…”

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confidence: 99%

Methicillin Resistance in Staphylococcus pseudintermedius Isolated from Shelter Dogs in Turkey

Sareyyüpoğlu¹,

Müştak²,

Cantekin³

et al. 2014

Kafkas Univ Vet Fak Derg

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SummaryStaphylococcus pseudintermedius is a recently described species of staphylococci that is frequently isolated from dogs. The increase in antimicrobial resistance in staphylococci and transfer of S. pseudintermedius from infected pets to humans threaten the public health worldwide. In this study, it was aimed to determine the prevalence of S. pseudintermedius from skin infections of dogs and to determine the prevalence of methicillin-resistance in S. pseudintermedius isolates by phenotypic and genotypic methods. A total of 41 staphylococci were isolated from 53 dogs. Thirty three (80.4%) staphylococci were identified as S. pseudintermedius by PCR-RFLP analysis of pta gene. Methicillin resistance was also identified in 11 (33.3%) of these isolates by inoculation on chromogenic chromID MRSA agar, oxacillin disc diffusion method and the determination of mecA gene by PCR. This is the sole report in Turkey that described the situation of methicillin resistant S. pseudintermedius. Keywords: Dog, Staphylococcus pseudintermedius, Methicillin resistance Türkiye'deki Barınak Köpeklerinden İzole Edilen Staphylococcus pseudintermedius'larda Metisilin Direnci ÖzetStaphylococcus pseudintermedius, stafilokoklar içerisinde yeni tanımlanmış bir tür olup köpeklerden sıklıkla izole edilmektedir. Stafilokoklarda artan antimikrobiyal direnç ve S. pseudintermedius'un enfekte petlerden insanlara geçmesi, halk sağlığını tehdit etmektedir. Bu çalışmada, köpek deri enfeksiyonlarından izole edilen S. pseudintermedius'ların ve metisilin direncinin prevalansının fenotipik ve genotipik metotlar ile belirlenmesi amaçlanmıştır. Toplam 53 köpekten 41 stafilokok izole edildi. Stafilokok izolatlarının 33'ü (%80.4) pta geninin PCR-RFLP ile analiziyle S. pseudintermedius olarak belirlendi. Metisilin direnci kromogenik chromID MRSA agar, oxacillin disk difüzyon metodu ve mecA geninin belirlendiği PCR yöntemi ile bu izolatların 11'inde (%33.3) tespit edildi. Bu çalışma, Türkiye'de metisilin dirençli S. pseudintermedius'ların durumunu gösteren ilk bilimsel rapordur.

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“…S. pseudintermedius is the principal cause of pyoderma and otitis in canine [24]. Although it had been misidentified for decades as S. intermedius, recent analyses by molecular phylogenetic and PCR-restriction fragment length polymorphism (PCR-RFLP) approaches indicated that S. pseudintermedius, not S. intermedius, is the major canine pyoderma pathogen [6,23,25], and it has already been proposed that all strains from dogs identified by traditional means be reported as S. pseudintermedius [6,11]. Increasing resistance of this organism and failures to treat canine pyoderma or otitis with a number of antibacterial agents, including fluoroquinolones were reported recently [6,30].…”

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The <i>In Vitro</i> Activity of 15 Antimicrobial Agents against Bacterial Isolates from Dogs

et al. 2012

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ABSTRACT. The in vitro activity of 15 antimicrobial agents against clinical isolates of Staphylococcus pseudintermedius, Staphylococcus aureus, Escherichia coli, Pasteurella spp. and Streptococcus canis from dogs was investigated. For Staphylococcus spp., the highest frequency of resistance was observed for penicillin, followed by ampicillin, tetracycline and chloramphenicol. The highest frequency of resistance in E. coli isolates was recorded for tetracycline and streptomycin. Pasteurella spp. and S. canis had the highest resistance rate for tetracycline and chloramphenicol. Most isolates showed full susceptibility to low-level resistance to colistin, florfenicol and fluoroquinolones. Further studies using larger number of isolates from both healthy and diseased dogs would provide a broader picture of antimicrobial resistance at a national level and promote prudent use of antimicrobial agents in companion animals. Antibacterial drug resistance continues to increase worldwide, with some pathogenic bacteria exhibiting resistance to virtually all available drugs [29]. While there are considerable, though often fragmented, data on the quantities of antimicrobial drug use and resistance in bacteria of food animal origin, useful data on antimicrobial drug use and resistance in companion animals are relatively scarce [22,24]. The most frequent bacterial infections in dogs include skin, ear, wound, gastrointestinal and urinary tract infections. Staphylococcus pseudintermedius, Escherichia coli, Pseudomonas aeruginosa, Streptococcus spp. and Proteus spp. are among the most frequently encountered bacterial pathogens in companion animal veterinary practice. The antimicrobial drug susceptibilities of canine isolates have been reported [1,7,9,23], most of which have also zoonotic significance. S. pseudintermedius is the principal cause of pyoderma and otitis in canine [24]. Although it had been misidentified for decades as S. intermedius, recent analyses by molecular phylogenetic and PCR-restriction fragment length polymorphism (PCR-RFLP) approaches indicated that S. pseudintermedius, not S. intermedius, is the major canine pyoderma pathogen [6,23,25], and it has already been proposed that all strains from dogs identified by traditional means be reported as S. pseudintermedius [6,11]. Increasing resistance of this organism and failures to treat canine pyoderma or otitis with a number of antibacterial agents, including fluoroquinolones were reported recently [6,30]. Furthermore, cross-resistance between fluoroquinolones and other antibacterial agents and zoonotic transmission of both meticillin-susceptible and meticillin-resistant S. pseudintermedius between dogs and humans have been concerns recently [30,31]. Resistance in canine E. coli isolates to a wide range of antimicrobial agents, including fluoroquinolones, is increasingly reported [2]. Furthermore, the chemical and structural similarities between veterinary and human-use drugs and the close phylogenetic relationships between E. coli isolates from dogs and man have r...

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Transmission of multiple antimicrobial-resistant Staphylococcus intermedius between dogs affected by deep pyoderma and their owners

Cited by 186 publications

References 19 publications

Prevalence ofStaphylococcus aureuscarriage among dogs and their owners

Prevalence ofStaphylococcus aureuscarriage among dogs and their owners

Methicillin Resistance in Staphylococcus pseudintermedius Isolated from Shelter Dogs in Turkey

The <i>In Vitro</i> Activity of 15 Antimicrobial Agents against Bacterial Isolates from Dogs

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