Transnasal Esophagoscopy: White-Light versus Narrowband Imaging

O’Brien, Timothy J.; Parham, Kourosh

doi:10.1177/000348940811701204

Cited by 7 publications

(11 citation statements)

References 18 publications

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“…Inspection of the mucosa is performed by pulling the endoscope slowly upward in a circumferential manner. For inspection of the esophagus, air is blown through the working channel to open the esophagus . The gastrointestinal junction is difficult to inspect and requires more time.…”

Section: Resultsmentioning

confidence: 99%

“…For inspection of the esophagus, air is blown through the working channel to open the esophagus. 4,6,7,[15][16][17][18]20,21,24,25,29,[31][32][33][37][38][39]42,43,[47][48][49][50]52,57,[63][64][65][66] The gastrointestinal junction is difficult to inspect and requires more time. The caudal portion of the gastrointestinal junction can be visualized by passing the endoscope in the gastric cardia and by performing a retroflexion of the tip of the endoscope up to 210 8, although not all endoscopes possess this feature.…”

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confidence: 99%

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Office-based procedures for diagnosis and treatment of esophageal pathology

et al. 2017

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Section: Resultsmentioning

confidence: 99%

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confidence: 99%

Office-based procedures for diagnosis and treatment of esophageal pathology

et al. 2017

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“…The total number of the patients assessed in the studies was 502 (range per study 11–173), who had 3988 (35–1190) lesions assessed with NBI and compared with histopathology. Seven of the excluded studies were interobesever studies with no data available on true negatives or false positives for calculating sensitivity and specificitity . Three other excluded studies were not in accordance with the inclusive criteria .…”

Section: Resultsmentioning

confidence: 99%

“…Seven of the excluded studies were interobesever studies with no data available on true negatives or false positives for calculating sensitivity and specificitity. [20][21][22][23][24][25][26] Three other excluded studies were not in accordance with the inclusive criteria. [27][28][29] Five studies gave details of HGD or SIM characterization on a per-patient analysis, 9,[15][16][17] and five studies revealed data for per-lesion basis.…”

Section: Description Of the Study Characteristicsmentioning

confidence: 99%

Meta-analysis of the effects of endoscopy with narrow band imaging in detecting dysplasia in Barrett's esophagus

et al. 2014

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Narrow band imaging (NBI) is a real-time imaging technique. The aim of this meta-analysis was to estimate the sensitivity, specificity, and diagnostic accuracy on the role of NBI in the detection and characterization of specialized intestinal metaplasia (SIM), high-grade dysplasia (HGD) in the Barrett's esophagus. We identified studies by performing a literature search of Medline, EMBASE, and the Cochrane Library databases up to May 2013. We performed data analysis using Meta-DiSc (version 1.4) software. To assess study quality and potential for bias, we used the Quality Assessment of Diagnostic Accuracy Studies-2 tool (QUADAS-2). Overall, seven eligible studies including over 3988 lesions of 502 patients were retrieved. The results showed that endoscopic diagnosis of dysplasia performed using NBI has a high diagnostic performance, with an area under the summary receiver operating characteristic (SROC) curve near 0.90 both in HGD lesions and SIM lesions. We also found that NBI has a sensitive and specificity of 0.91 (95% confidence interval [CI] = 0.86-0.94) and 0.85 (95% CI = 0.76-0.92) on a per-patient element, and 0.97 (95% CI = 0.95-0.98) and 0.64 (95% CI = 0.59-0.68) on a per-lesion element for SIM diagnosis, respectively. The pooled per-patient sensitivity and specificity for identifying HGD are 0.91 (95% CI = 0.75-0.98) and 0.95 (95% CI = 0.91-0.97). The pooled per-lesion sensitivity and specificity for identifying HGD are 0.69 (95% CI = 0.63-0.74) and 0.90 (95% CI = 0.88-0.91). In conclusion, we found that endoscopic diagnosis with NBI is an accurate test to diagnosis dysplasia of Barrett's esophagus.

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“…A recent report of sidestream dark-field video microscopy identified alterations in the oral mucosal microvasculature circulation that could represent an important mechanism of early tissue injury35. Narrow band imaging is an optical filter technology that can differentiate between deep and shallow blood vessels, which could provide additional insight into mucosal-based change secondary to cancer therapy36, 37.…”

Section: Imaging Technologymentioning

confidence: 99%

Oral mucositis: the new paradigms

Peterson

Lalla

2010

Current Opinion in Oncology

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Purpose of review Mucositis has long been viewed as an unavoidable consequence of high-dose chemotherapy and/or radiation. Management has been directed to supportive care including oral pain control, nutritional support, infection treatment and control of diarrhea. While these interventions have been valuable for clinical management, they have not been collectively directed to molecularly targeted prevention and treatment. This review addresses recent advances regarding mucosal injury in cancer patients, with emphasis on symptom clusters, genetically-based tissue susceptibility and risk prediction, imaging technology, and computational biology. Recent findings Modeling of symptom clusters in cancer patients continues to mature. Although integration of mucositis into the paradigm is at an early stage, recent reports suggest that important molecular and clinical insights will emerge in this regard. Initial studies of genetic-based tissue risk are also providing a research basis that may lead to clinical risk prediction models. These advances are in part being engineered via new imaging and computational biology technologies, drawing upon literature in non-mucositis systems. Just as the past decade has been hallmarked by linkage of pathobiology with clinical expression of mucosal toxicity, the next decade promises to identify new molecular interactions and risk prediction models based on novel application of the analytic technologies. Summary Recent research has culminated in convergence of molecular pathobiology with models of symptom clusters, genetic-based risk, and imaging and computational biology. The field is poised to further delineate this paradigm, with the goal of development of molecularly targeted drugs and devices for mucositis management.

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Transnasal Esophagoscopy: White-Light versus Narrowband Imaging

Abstract: Narrowband imaging may be a useful adjunct in increasing the diagnostic sensitivity of TNE in the hands of the otolaryngologist.

Cited by 7 publications

References 18 publications

Office-based procedures for diagnosis and treatment of esophageal pathology

Office-based procedures for diagnosis and treatment of esophageal pathology

Meta-analysis of the effects of endoscopy with narrow band imaging in detecting dysplasia in Barrett's esophagus

Oral mucositis: the new paradigms

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