2014
DOI: 10.1002/hed.23688
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Transoral laser microsurgery for T1a glottic cancer: Review of 404 cases

Abstract: Low complication rates, excellent functional outcome, and high rates of organ preservation favor TLM. In agreement with the literature, TLM should be the treatment of choice for patients presenting with T1a glottic SCC.

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Cited by 104 publications
(97 citation statements)
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“…In the past 25 years, TLM has largely supplanted open conservation laryngeal surgery, with pioneers of the technique showing early on that complete, oncologically sound resection is possible transorally with low morbidity and without diminished oncologic outcomes. [20][21][22][23][24][25] Technological advances in laryngeal microscopy and lasers have facilitated access to this type of surgery, which is now considered the gold standard for treatment of early glottic cancer. 26 Transoral laser resection is based on à la carte resection, after tumor spread and sparing noninvolved structures, contrary to other techniques in which resection follows anatomic landmarks rather than following the tumor itself.…”
Section: Transoral Laser Microsurgerymentioning
confidence: 99%
“…In the past 25 years, TLM has largely supplanted open conservation laryngeal surgery, with pioneers of the technique showing early on that complete, oncologically sound resection is possible transorally with low morbidity and without diminished oncologic outcomes. [20][21][22][23][24][25] Technological advances in laryngeal microscopy and lasers have facilitated access to this type of surgery, which is now considered the gold standard for treatment of early glottic cancer. 26 Transoral laser resection is based on à la carte resection, after tumor spread and sparing noninvolved structures, contrary to other techniques in which resection follows anatomic landmarks rather than following the tumor itself.…”
Section: Transoral Laser Microsurgerymentioning
confidence: 99%
“…Definitive radiation therapy (RT) and surgery are both valid, commonly used therapeutic options for the primary treatment of these tumors. To date, however, no studies have directly and prospectively compared these treatments, the choice being determined by treatment availability and local expertise [2][3][4]. The primary reported advantage of RT is preservation of a better voice [5].…”
Section: Introductionmentioning
confidence: 97%
“…Research to date on this subject is best summarized as involving (1) cadaveric modeling to assess the feasibility of these approaches to access the deep recesses of the midface and sub skull base [14]; (2) comprehensive meta-analysis and systematic review [15] and (3) clinical outcome studies [16].…”
Section: Discussionmentioning
confidence: 99%