2017
DOI: 10.1002/biot.201700334
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Transparent Substrates Prepared From Different Amorphous Polymers Can Directly Modulate Primary Human B cell functions

Abstract: Manipulation of B cell functions such as antibody and cytokine secretion, is of clinical and biotechnological interest and can be achieved by soluble ligands activating cell surface receptors. Alternatively, the exposure to suitable solid substrates would offer the possibility to transiently induced cell signaling, since the signaling is interrupted when the cells are removed from the substrate. Cell/substrate interactions are mediated by physical valences such as, hydrogen bonds or hydrophobic forces on the s… Show more

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