Transperineal aggressive angiomyxoma

Pereira, Pedro; Abreu, Elisa; Cunha, Teresa Margarida; Rolim, Inês

doi:10.1136/bcr-2016-217705

Cited by 5 publications

(5 citation statements)

References 16 publications

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“…Because of the rarity of the AA, preoperative diagnosis is often difficult and a lot of cases are diagnosed on histological findings after the surgical excision. 11,12 Macroscopically the surface of tumor is smooth, partially or completely encapsulated, lobular, with borders that are not well circumscribed. 11 Histologically the tumor demonstrates stellate-to-spindle shaped cells distributed sparsely throughout the myxoid stroma and aggregated around blood vessels.…”

Section: Discussionmentioning

confidence: 99%

Aggressive Angiomyxoma of the Perineum: A Rare Case Entity and Literature Review

Pandita

Bashir

Sharma

et al. 2019

ASJO

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Angiomyxomas are soft tissue tumors that are exceedingly rare with very few cases described in literature. They are classified into a less aggressive superficial variant and a deeper aggressive variant commonly called aggressive angiomyxomas (AA). The cross-sectional imaging, particularly magnetic resonance imaging (MRI), plays an essential role in the diagnosis and management of AA. We report a rare case of Aggressive angiomyxoma in a 28-year-old female. AbstractKeywords ► aggressive angiomyxoma ► radiotherapy ► hormonal therapy

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Section: Discussionmentioning

confidence: 99%

Aggressive Angiomyxoma of the Perineum: A Rare Case Entity and Literature Review

Pandita

Bashir

Sharma

et al. 2019

ASJO

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“…The nodule can be mistaken as a lipoma, Bartholin's or Gartner's duct cyst, abscess or even as a malignant pelvic floor tumor. Because of the rarity of the aggressive angiomyxoma pre-operative diagnosis is difficult and a lot of cases are diagnosed on histological findings after the surgical excision [6,18].…”

Section: Discussionmentioning

confidence: 99%

“…But in the published data the influence of tumor-free margins is not clear. Complete resection is important, but when the operative morbidity is too high or the preservation of the fertility is necessary incomplete resection seems to be acceptable [8,18]. It is recommended to treat the tumor at an initial stage, when complete resection is possible.…”

Section: Discussionmentioning

confidence: 99%

“…In the literature gonadotropin-releasing hormone (GnRH) agonists is the recommended hormonal treatment in premenopausal women. The response to gonadotropinreleasing hormone (GnRH) agonists varies, because the estrogen and progesterone receptors are not always strongly positive in aggressive angiomyxoma [15][16][17][18]. There exist no data of the optimal duration of the therapy [27].…”

Section: Discussionmentioning

confidence: 99%

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Aggressive Angiomyxoma of the Perineum in a 50-Year-Old Woman: Case Report and Current Level of Education

Keller¹,

Schmid²,

Monod³

et al. 2018

Gynecol Obstet Case Rep

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Background: Aggressive angiomyxoma is a rare soft tissue mesenchymal tumor, locally infiltrative with a tendency to repeated local recurrence. The first description was in 1983. Normally it occurs in the vulvovaginal region, perineum and pelvis of females in reproductive age. Local wide excision of the tumor is the primary management. The local recurrence rate is high. The expression of estrogen and progesterone receptors in aggressive angiomyxoma suggests a hormone dependency of the tumor. Case report:A 50-year-old woman reported first in 2013 with a painless swelling at the perineum. She underwent surgical excision. Pathologic findings reported the tumor as an aggressive angiomyxoma. The patient did not appear to the follow-up examinations. In 2016 she reported again with a painless swelling at the perineum and underwent a local wide resection. The perineal body had to be reconstructed because of the deep infiltration of the tumor. Conclusion:Aggressive angiomyxoma is a rare disease, but when treating women with a painless swelling in the vulvovaginal region, perineum or pelvis aggressive angiomyxoma should be considered as a differential diagnosis. There is no standardised therapy described, but complete resection seems to be important. Descriptions of pharmacologic treatment exist with gonadotropinreleasing hormone agonists.

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“…Considering of its high local recurrence and characteristic of aggressive, a complete surgical excision is very important [6], which patients will get benefit from it. Tumor-free margin surgical excision is considered as a usual way to get the treatment.…”

Section: Case Presentationmentioning

confidence: 99%

Recurrent transperineal aggressive angiomyxoma: a case report

Zhou

Lin

2021

Preprint

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Background: aggressive angiomyxoma is a rare disease that may cause misdiagnosed in the clinical work and the characteristic of this disease is low potential malignancy. This case show a recurrent case of aggressive angiomyxoma 7 years after the surgery which was mistakenly diagnosed at that time.Case presentation: the patient presented a large mass in the right labium majus without any pain. This mass was recurrent 7 years after she received a surgery about the mass occurred at the same place which was diagnosed as vulvar angiomyofibroblastoma. She took the ultrasound scan and MRI scan and underwent the surgery again. This mass was excision completely. At this time, pathologist checked the HE stained slides and immunohistochemistry staining slides, then come the conclusion that this mass was aggressive angiomyxoma. We rechecked the pathological slides 7 tears ago and found out it was misdiagnosed at that time.Conclusions: Aggressive angiomyxoma is a rare tumor. This case presents a rare disease that may be misdiagnosed as other benign vulvar disease even after the surgery which get pathologic evidence. So we need to know more abou this disease.

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Transperineal aggressive angiomyxoma

Cited by 5 publications

References 16 publications

Aggressive Angiomyxoma of the Perineum: A Rare Case Entity and Literature Review

Aggressive Angiomyxoma of the Perineum: A Rare Case Entity and Literature Review

Aggressive Angiomyxoma of the Perineum in a 50-Year-Old Woman: Case Report and Current Level of Education

Recurrent transperineal aggressive angiomyxoma: a case report

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