Transperineal template‐guided prostate biopsy: 10 years of experience

Mai, Zhipeng; Yan, Weigang; Zhou, Yi; Zhou, Zhien; Chen, Jian; Xiao, Yu; Liang, Zhiyong; Ji, Zhigang; Li, Hanzhong

doi:10.1111/bju.13024

Cited by 22 publications

(20 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Over the past 10 years, we have completed more than 5000 cases of template-guided transperineal prostate biopsies and proposed our own perspective regarding the spatial distribution of prostate cancer on prostate biopsy [ 4 – 6 ]. Confirmation using radical prostatectomy specimens is the most reliable method for verifying the accuracy of template-guided transperineal prostate biopsy [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

The transverse and vertical distribution of prostate cancer in biopsy and radical prostatectomy specimens

et al. 2018

Self Cite

View full text Add to dashboard Cite

BackgroundProstate biopsy is the most common method for the diagnosis of prostate cancer and the basis for further treatment. Confirmation using radical prostatectomy specimens is the most reliable method for verifying the accuracy of template-guided transperineal prostate biopsy. The study aimed to reveal the spatial distribution of prostate cancer in template-guided transperineal saturation biopsy and radical prostatectomy specimens.MethodsBetween December 2012 to December 2016, 171 patients were diagnosed with prostate cancer via template-guided transperineal prostate biopsy and subsequently underwent laparoscopic radical prostatectomy. The spatial distributions of prostate cancer were analyzed and the consistency of the tumor distribution between biopsy and radical prostatectomy specimens were compared.ResultsThe positive rate of biopsy in the apex region was significantly higher than that of the other biopsy regions (43% vs 28%, P < 0.01). In radical prostatectomy specimens, the positive rate was highest at the region 0.9–1.3 cm above the apex, and it had a tendency to decrease towards the base. There was a significant difference in the positive rate between the cephalic and caudal half of the prostate (68% vs 99%, P < 0.01). There were no significant differences between the anterior and posterior zones for either biopsy or radical prostatectomy specimens.ConclusionThe tumor spatial distribution generated by template-guided transperineal prostate biopsy was consistent with that of radical prostatectomy specimens in general. The positive rate was consistent between anterior and posterior zones. The caudal half of the prostate, especially the vicinity of the apex, was the frequently occurred site of the tumor.

show abstract

Section: Introductionmentioning

confidence: 99%

The transverse and vertical distribution of prostate cancer in biopsy and radical prostatectomy specimens

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…These misses might have occurred because larger prostates may be shielded by the pubic arch. [ 8 ] To avoid this, we did not use the template and punctured obliquely upward in patients with pubic arch occlusion, [ 8 ] which however, lowered the accuracy. The efficacy of biopsy in this area would be enhanced with MRI.…”

Section: Discussionmentioning

confidence: 99%

“…TTPSB was performed in 11 regions. [ 8 ] The Bard Biopsy gun (C.R. Bard, Inc., Covington, GA) and an 18-gauge biopsy needle were used to obtain biopsy cores transperineally through the template.…”

Section: Methodsmentioning

confidence: 99%

Diagnostic accuracy of magnetic resonance-guided prostate biopsy and template-guided transperineal saturation biopsy

Zhou¹,

Zhou

et al. 2018

Medicine

Self Cite

View full text Add to dashboard Cite

To compare the accuracy of magnetic resonance-guided prostate biopsy (MR-GPB) and template-guided transperineal prostate saturation biopsy (TTPSB).A total of 219 patients with elevated prostate-specific antigen, abnormal digital rectal examination or ultrasound findings were enrolled. All patients underwent multiparametric magnetic resonance image (mpMRI). Patients with a Prostate Imaging Reporting and Data System (PI-RADS) score of 3 to 5 underwent MR-GPB using 2 to 5 biopsy cores and then immediately underwent an 11-region TTPSB. Patients with a PI-RADS score of 1 to 2 underwent TTPSB alone. We compared the detection rates for any cancer, clinically significant prostate cancer (csPCA), and the spatial distribution of missed csPCA lesions.Among the 219 cases, 66 (30.1%) had a PI-RADS score of 1 to 2 on mpMRI. The detection rate of TTPSB in these patients was 9.1% (6/66). In total, detection rates for any cancer and csPCA were 48.9% (107/219) and 42.9% (94/219), respectively. Detection rates for any cancer (TTPSB 87/219, 39.7%; MR-GPB76/219, 34.7%, P = .161) and csPCA (TTPSB 76/219, 34.7%; MR-GPB 72/219, 32.9%, P = .636) did not significantly differ between the 2 groups. The csPCA lesions missed by MR-GPB were most commonly located on the left (8.5%, 8/94) and right (9.6%, 9/94) sides of the urethra.MR-GPB can reduce the rate of unnecessary prostate biopsies by approximately 30% and exhibits an efficacy comparable to TTPSB for the detection of any cancer and csPCA. Nevertheless, approximately 1/4 of csPCAs were missed by MR-GPB and were most commonly located on both sides of the urethra.

show abstract

“…However, our study reported the 39.3% PCDR, higher than that of study by Mai et al . (35.5%) [17]. The difference was possibly originated from different inclusion criteria.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of prostate cancer detection rate (PCDR) in Chinese Han population under different prostate biopsy methods

et al. 2017

View full text Add to dashboard Cite

We analyzed the improvement of prostate cancer detection rate (PCDR) in Chinese Han population and summarized the characteristics of prostate cancer (PCa) with the advancement of prostate biopsy technologies. From March 1999 to March 2015, 3762 patients underwent the systematic 6-, 8- or 13-core biopsy, guided by finger or transrectal ultrasound (TRUS) at our center. The PCDR under different PSA intervals and different biopsy methods were analyzed. The trends of PSA level, age and Gleason score of PCa patients were summarized. The PCDR of finger-guided 6- and 8-core biopsies were 30.8% (340/1103) and 36.7% (147/401) respectively. In 2258 patients with TRUS-guided 13-core biopsies, 992 (43.9%) were diagnosed as PCa, higher than that with finger-guided biopsies (43.9% vs. 32.4%, p < 0.001). The PCDR of prostate peripheral zone was higher than that of medial zone (37.5% vs. 31.4%, p < 0.001). Interestingly, the PCDR of extra 13th core was higher than the mean positive rate of other 12 cores (70.7% vs. 56.0%, p < 0.001). The systematic 13-core prostate biopsy guided by TRUS is safe, effective, and economic for PCa diagnosis in developing countries like China. The extra 13th core biopsy is beneficial to increase the PCDR.

show abstract

Transperineal template‐guided prostate biopsy: 10 years of experience

Cited by 22 publications

References 22 publications

The transverse and vertical distribution of prostate cancer in biopsy and radical prostatectomy specimens

The transverse and vertical distribution of prostate cancer in biopsy and radical prostatectomy specimens

Diagnostic accuracy of magnetic resonance-guided prostate biopsy and template-guided transperineal saturation biopsy

Characteristics of prostate cancer detection rate (PCDR) in Chinese Han population under different prostate biopsy methods

Contact Info

Product

Resources

About