Transperineal versus transrectal multi-parametric magnetic resonance imaging fusion targeted prostate biopsy

Abstract

‫املهم‬ ‫السرطان‬ ‫اكتشاف‬ ‫ومعدل‬ ‫احلالة‬ ‫اكتشاف‬ ‫معدل‬ ‫من‬ ‫كل‬ ‫كان‬ ، ‫ذلك‬ ‫ومع‬ 45.1%( ‫بنسبة‬ TRUSBx ‫مقابل‬ TPBx ‫في‬ ‫ملحوظ‬ ‫بشكل‬ ‫أعلى‬ ‫ا‬ ً ‫سريري‬ ‫على‬ ‫؛‬ p=0.002 ، 43.7% ‫مقابل‬ 71.8% ‫و‬ ‫؛‬ p=0.003 ، 29.1% ‫مقابل‬ 41.2( ‫مبعدل‬ TRUSBx ‫في‬ ‫أطول‬ ً ‫وقتا‬ ‫العجان‬ ‫عبر‬ ‫اخلزعات‬ ‫استغرقت‬ ‫التوالي).‬ .)p=0.0001 ، ‫دقيقة‬ 13±2.3 ‫مقابل‬ ‫دقيقة‬ 0.7 ± ‫ومع‬ ‫اإلجراءين.‬ ‫بني‬ ‫املضاعفات‬ ‫معدل‬ ‫في‬ ‫اختالف‬ ‫عن‬ ‫الكشف‬ ‫يتم‬ ‫لم‬ ‫اخلالصة:‬ ‫واكتشاف‬ ‫عام‬ ‫بشكل‬ ‫السرطان‬ ‫عن‬ ‫الكشف‬ ‫في‬ ‫فعالية‬ ‫أكثر‬ TPBx ‫كان‬ ‫ذلك،‬ ‫خاص.‬ ‫بشكل‬ ‫ا‬ ً ‫سريري‬ ‫املهم‬ ‫السرطان‬ Objectives: To compare transperineal biopsies (TPBx) with transrectal ultrasound-guided biopsy (TRUSBx) in order to provide evidence, making clinicians able to select the appropriate biopsy approach under different conditions.

Initial Outcomes of Freehand Transperineal Biopsies Regarding Diagnostic Value and Safety: An Early Experience at King Fahad Specialist Hospital, Buraydah, Saudi Arabia

“…In our sample, prostate volume was 73.5 ml (SD 47.5) which is comparable and in the range of other reports [15,20,21]. The mean PSA was 36.6 ng/ml (SD 39), which is higher than other similar studies like Takenaka et al [21], Cerruto et al [20], Rabah et al [15], with their PSA results being (17.1±30.1), (15.95±41.04), (14.2±5) ng/ml, respectively.…”

“…In our sample, prostate volume was 73.5 ml (SD 47.5) which is comparable and in the range of other reports [15,20,21]. The mean PSA was 36.6 ng/ml (SD 39), which is higher than other similar studies like Takenaka et al [21], Cerruto et al [20], Rabah et al [15], with their PSA results being (17.1±30.1), (15.95±41.04), (14.2±5) ng/ml, respectively. This high mean PSA might be attributed to the delayed presentation due to the lack of information and utilization of screening tests in our community, as suggested by Arafa and Rabah [26].…”

“…The complication rate was 5.1% of those who did TPBx, with only one patient who had retrograde ejaculation and the other having hematuria. These results are similar to Rabah et al (6.3%), Di Franco et al (4%), and Halpern et al (5.4%) reports, with hematuria and urinary retention being the most common complications in all of them [ 15 , 18 , 25 ]. However, with Huang et al complication rate reached 15.3% [ 22 ].…”

“…The same study compared the problems between the two techniques, finding that hematuria and urinary retention were the most often found issues in both groups, with no discernible difference between them. The clear distinction was that 3.6% of patients reported rectal bleeding following trans-rectal biopsy [ 15 ]. Based on the experience of King Fahad Specialist Hospital in Buraydah, Qassim region, Saudi Arabia, this study aims to determine the initial outcomes of freehand TPBx in terms of diagnostic value and safety.…”

“…It leads to a significantly lower incidence of infection-related consequences, with sepsis rates close to zero [13,14]. TPBx has some obvious drawbacks, including a longer duration than TRUSBx and a higher rate of post-procedure pain complaints [15,16]. Although numerous studies were conducted comparing the TPBx and TRUSBx techniques' detection rates, the conclusions of the two approaches' respective detection rates were controversial [17][18][19].…”