Transplantation in and of the Young

Merkel, Frederick K.; Ing, Todd S.; Ahmadian, Y.; Lewy, Peter; Ambruster, Kent; Oyama, J.; Sulieman, J. Samir; Belman, A. Barry; King, Lowell R.

doi:10.1016/s0022-5347(17)60046-6

Cited by 18 publications

(2 citation statements)

References 8 publications

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“…En b loe tra nsplan ta t io n of both kidn eys from p ae dia t ric donors (Fig. 3 ) is on ly to bc cm p loycd whcn dealin g w it h t h e ex t re mc ly sm all kidneys o f dono rs under t w o y ca rs of age (1,3,7, 10,1 1, 12,13). This m ethod provid es an imm edi ate n eph ron mass mo re closcly approximatin g the needs of t he reeip ient.…”

Section: Resultsmentioning

confidence: 99%

The Use of Paediatric Cadaver Kidneys for Transplantation in Adult Recipients

Vliet¹,

Kootstra²,

Tegzess³

et al. 1981

Eur J Pediatr Surg

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In view of the shortage of cadaveric donors a retrospective study has been performed to determine the results of transplantation of paediatric cadaver donor kidneys into adult recipients. Graft- and patient survival and renal function in the 31 cases analysed in this study showed no adverse effect of the use of paediatric donor kidneys. No vascular complications were encountered. Ureteric leakage occurred in only one case and it was treated successfully. It is concluded that paediatric age is no criterion for donor exclusion and that paediatric donors are to be regarded as a valuable source of cadaveric kidneys for transplantation.

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Section: Resultsmentioning

confidence: 99%

The Use of Paediatric Cadaver Kidneys for Transplantation in Adult Recipients

Vliet¹,

Kootstra²,

Tegzess³

et al. 1981

Eur J Pediatr Surg

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“…In the following decade, the number of paediatric donor kidneys increased but the quality of the organs was generally considered as poor with a relatively short graft survival and a high incidence of complications. In 1974, it was concluded from an analysis of the American College of Surgeons/National Institutes of Health Transplant Registry (ACS/NIH) database that these kidneys had an inferior but, given a shortage of donor organs, acceptable level of function in adults [42]. Since then, improved transplantation techniques and superior immunosuppression have improved the results of transplantation from paediatric donor kidneys, so that, apart from kidneys from donors younger than 5 years, this group of kidneys is increasingly seen as a valuable expansion of the donor pool.…”

Section: Paediatric Donorsmentioning

confidence: 99%

Kidney transplantation and donation in children

Heurn

Vries

2009

Pediatr Surg Int

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It has been shown that kidney transplantation results in superior life expectancy and quality of life compared with dialysis treatment for patients with end-stage renal disease. However, kidney transplantation in children differs in many aspects from adult kidney transplantation. This review focuses on specific issues of surgical care associated with kidney transplantation in children, including timing of transplantation, technical considerations, patient and graft survival, growth retardation and post-transplant malignancy. At the same time, there is a large discrepancy between the number of available donor kidneys and the number of patients on the waiting list for kidney transplantation. There is a general reluctance to use paediatric donor kidneys, because of relatively frequent complications such as graft thrombosis and early graft failure. We review the specific aspects of kidney transplantation from paediatric donors such as the incidence of graft thrombosis, hyperfiltration injury and 'en bloc' transplantation of two kidneys from one donor with an excellent long-term outcome, which is comparable with adult donor kidney transplantation. We also discuss the potential use of paediatric non-heart-beating donor kidneys, from donors whose heart stopped beating with the preservation techniques used.

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Cognitive Effects of Acute and Chronic Pediatric Medical Conditions

Lehr

1984

Psychological and Behavioral Assessment

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Transplantation in and of the Young

Cited by 18 publications

References 8 publications

The Use of Paediatric Cadaver Kidneys for Transplantation in Adult Recipients

The Use of Paediatric Cadaver Kidneys for Transplantation in Adult Recipients

Kidney transplantation and donation in children

Cognitive Effects of Acute and Chronic Pediatric Medical Conditions

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