2015
DOI: 10.23937/2378-3648/1410015
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Transplantation of hBMSCs Loaded on Collagen Scaffolds for the Regeneration of Canine Tissue-Engineered Urethras

Abstract: Objective: To estimate the function of human bone marrow derived mesenchymal stem cells (hBMSCs) loaded on collagen scaffolds in the regeneration of canine tissue-engineered urethras. Methods:In this study, hBMSCs (1×10 6 hBMSCs per 1cm 2 collagen scaffold) were loaded on tubular collagen scaffolds (5cm in length). A 5cm long urethra segment near the penis bone was excised surgically. A collagen scaffold seeded with hBMSCs was sutured to two ends of the host urethra for the urethral repair in the experimental … Show more

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