Transplantation of hybrid adipose-derived stem cell sheet with autologous peritoneum: An in vivo feasibility study

Cell‐sheet delivery for wound healing through transfer‐tattoo approach: A new wound management era?

“…Sri Harsha Boppana 2 Karthikeya Reddy Ramasahayam 3 Jaya Surya Manimekalai Krishnamurthi 4 Ganesh Tummala 5 Snehasish Mishra 6 Ranjan K. Mohapatra 7 Md. Kudrat-E-Zahan 8 1…”

“…Cell types such as hepatocytes, fibroblasts, and endothelial cells have been grown and separated as cell sheets from the surface. 6 …”

The Role and Prospects of Mesenchymal Stem Cells in Skin Repair and Regeneration

“…Studies of skin pressure sore healing induced by the injection of MSC-based cell sheets (CSs) in C57Bl/6 mice found that, despite a brief retention of the CSs on the ulcer surface (3-7 days), there was an increase in granulation tissue (GT) thickness and increased vascular maturity, while at the same time, compared to the mesenchymal stromal cell (MSC) exosome group, the CSs had a unique function of skin repair using skin appendages [131]. Additionally, the use of the peritoneum as the support for the precise transplantation of ASC tablets to the back of SD rats had better effects on gross and histopathological repair than that of simply injecting the ASC tablets [132]. Compared with fibroblast tablets, complete tablets composed of amniotic mesenchymal stem cells have a higher tendency to disintegrate, and have the potential to treat burn wounds [133].…”

Clinical evaluation of the perception of post-trauma paresthesia in the mandible, using a biomimetic material: A preliminary study in humans

“…Regenerative medicine is an emerging field of biotechnology that combines various aspects of natural sciences, including cellular and molecular biology, materials science, bioengineering, chemistry and biochemistry, among others, in order to regenerate, repair or replace injured tissues [ 4 ]. One of these emerging fields is called “biomimetics”, which is an area of regenerative science that aims to study biological structures and their functions, mimicking them and creating alternative strategies for developing simple solutions to complex problems [ [8] , [9] , [10] ]. The selected strategy was to locally provide microelements capable of interacting with the intra and extracellular environment, thus promoting a favorable environment, capable of promoting the repair of the injured target tissue, reducing local oxidative stress, providing favorable conditions for cellular respiration and promoting growth of the injured target tissue.…”