Effective interventions for drug abusing adolescents are underutilized. Using an interrupted time series design, this study tested a multicomponent, multi-level technology transfer intervention developed to train clinical staff within an existing day treatment program to implement multidimensional family therapy (MDFT), an evidence-based adolescent substance abuse treatment. The sample included 10 program staff and 104 clients. MDFT was incorporated into the program and changes were noted in the program environment, therapist behavior, and in most (e.g., drug abstinence, and out of home placements) but not all (e.g., drug use frequency) client outcomes. These changes remained after MDFT supervision was withdrawn. (Am J Addict 2006;15:102-112) Science-based, effective therapies have been developed to treat adolescent drug abuse, 1 but the practice of these treatments in community drug treatment clinics remains the exception rather than the rule. 2 This continuation of the research-practice divide is particularly troubling given what we are learning about the standard treatment that is available for most drug involved adolescents. Most adolescent treatment programs in standard community-based programs are plagued by high drop out rates, service fragmentation, and failure to address youths' multiple problems. For instance, a national multi-site evaluation of teen drug abuse treatment programs, found only 27% of youth completing outpatient therapy, and, according to these data the use of hard drugs increased over the course of treatment.3 Providers are unable to meet the needs of substance abusing youth with multiple problems, including those with comorbid disorders and legal involvement. These circumstances have commanded the attention of policy makers, managed care organizations, third-party payers, and local, state, and federal funding agencies to expedite the movement of research-based adolescent drug treatments to community settings. 4 But dire need does not mean that the task is simple. Transporting research-based therapies to non-research environments is complex and difficult. 5 We have learned a great deal about the challenges of this kind of work. Although effective, characteristics of the models themselves and provider factors interact to create formidable obstacles to adoption of science-based treatments. Treatments developed for research purposes are not generally designed to accommodate to the features of community clinics. Therapists in community clinics typically handle large caseloads, and do not receive clinical supervision that addresses their clinical development. Although interested in new therapies that could enhance their skill and effectiveness, community clinicians feel overburdened, and have few incentives or opportunities to learn manual-guided treatments. Systemic factors are at play as well. Community-based treatment programs rarely have an organizational structure, the financial resources and=or reimbursement system to implement new treatments.Still, solutions, or at least recommenda...