Transrectal robotic natural orifice translumenal endoscopic surgery (NOTES) applied to intestinal anastomosis in a porcine intestine model

Demura, Yoshitaka; Ishikawa, Norihiko; Hirano, Yasumitsu; Inaki, Noriyuki; Matsunoki, Aika; Watanabe, Go

doi:10.1007/s00464-013-3117-y

Cited by 7 publications

(5 citation statements)

References 31 publications

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“…However, we feel that the results after anastomosis by L-SST would most likely mimic the results of conventional SST. Leak tests are the most objective test for assessing anastomosis techniques and are widely used to determine the robustness of the anastomoses [19][20][21].…”

Section: Discussionmentioning

confidence: 99%

A novel single-stapling technique for colorectal anastomosis: a pre-ligation single-stapling technique (L-SST) in a porcine model

et al. 2014

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Section: Discussionmentioning

confidence: 99%

A novel single-stapling technique for colorectal anastomosis: a pre-ligation single-stapling technique (L-SST) in a porcine model

et al. 2014

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“…Although porcine models are frequently used to evaluate novel surgical technologies , the resulting findings have to be interpreted with caution. Firstly, porcine liver histology differs from humans with more pronounced interlobular septations.…”

Section: Discussionmentioning

confidence: 99%

Utilizing confocal laser endomicroscopy for evaluating the adequacy of laparoscopic liver ablation

et al. 2015

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BackgroundLaparoscopic liver ablation therapy can be used for the treatment of primary and secondary liver malignancy. The increased incidence of cancer recurrence associated with this approach, has been attributed to the inability of monitoring the extent of ablated liver tissue.MethodsThe feasibility of assessing liver ablation with probe‐based confocal laser endomicroscopy (CLE) was studied in a porcine model of laparoscopic microwave liver ablation. Following the intravenous injection of the fluorophores fluorescein and indocyanine green, CLE images were recorded at 488 nm and 660 nm wavelength and compared to liver histology. Statistical analysis was performed to assess if fluorescence intensity change can predict the presence of ablated liver tissue.ResultsCLE imaging of fluorescein at 488 nm provided good visualization of the hepatic microvasculature; whereas, CLE imaging of indocyanine green at 660 nm enabled detailed visualization of hepatic sinusoid architecture and interlobular septations. Fluorescence intensity as measured in relative fluorescence units was found to be 75–100% lower in ablated compared to healthy liver regions. General linear mixed modeling and ROC analysis found the decrease in fluorescence to be statistically significant.ConclusionLaparoscopic, dual wavelength CLE imaging using two different fluorophores enables clinically useful visualization of multiple liver tissue compartments, in greater detail than is possible at a single wavelength. CLE imaging may provide valuable intraoperative information on the extent of laparoscopic liver ablation. Lasers Surg. Med. 48:299–310, 2016. © 2015 The Authors. Lasers in Surgery and Medicine Published by Wiley Periodicals, Inc.

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“…Small intestinal anastomosis was performed in a porcine intestinal Tr NOTES model using two robotic arms and a camera inserted through the proctoscope and a rectal anterior wall incision [120]. NOTES gastroenterostomy with a biflanged lumen-apposing stent was reported recently by collaboration of French and US centres.…”

Section: Small Bowel Notesmentioning

confidence: 99%

Natural Orifice Translumenal Endoscopic Surgery of the GastroIntestinal Tract

Hussain¹

2015

Endoscopy - Innovative Uses and Emerging Technologies

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Research Focus -NOTES is a new technique that faces numerous challenges. Current technology, training and research activities are conducted to make it a safe and effective minimal access technique.Research Methods Used -This chapter is based on the current evidence of published NOTES studies. Medline search is conducted through November to December , including English literatures only. The search words are NOTES, natural orifice translumenal endoscopic surgery, hybrid NOTES and hybrid natural orifice translumenal endoscopic surgery additional search words are specific for the titles like NOTES gastric, NOTES oesophageal, NOTES biliary, NOTES cholecystectomy, NOTES pancreatic, NOTES small bowel, NOTES colorectal and NOTES appendicectomy. "nimal and human studies are selected after . Small studies are excluded unless they report a novel approach or a new procedure.Results/Findings of the Research -There is development in the technology by installing new platforms, instruments and closure devices to add more safety and security. There is also development in training and research activities across the continents a number of NOTES procedures are performed safely on human beings including cholecystectomy, appendicectomy, peritoneoscopy, POEM and other procedures. Feasibility studies are conducted on animal and human cadaver models including numbers of complex procedures.Main Conclusions and Recommendations -NOTES is evolving and gaining popularity. The growth rate however is slowed by challenges of the need for an ideal working platform and closure devices that are easy to use, cheap and time effective, in addition to the dedicated effective training.

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Transrectal robotic natural orifice translumenal endoscopic surgery (NOTES) applied to intestinal anastomosis in a porcine intestine model

Abstract: Background Natural orifice translumenal endoscopic surgery (NOTES) is a minimally invasive

Cited by 7 publications

References 31 publications

A novel single-stapling technique for colorectal anastomosis: a pre-ligation single-stapling technique (L-SST) in a porcine model

A novel single-stapling technique for colorectal anastomosis: a pre-ligation single-stapling technique (L-SST) in a porcine model

Utilizing confocal laser endomicroscopy for evaluating the adequacy of laparoscopic liver ablation

Natural Orifice Translumenal Endoscopic Surgery of the GastroIntestinal Tract

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