Transrectal Ultrasound in the Diagnosis of Prostate Cancer: Location, Echogenicity, Histopathology, and Staging

Gray, Jerry M.; McLeary, R D; Meadows, T R; Kumasaka, G H; Borlaza, Gil S.; Straub, William; Lee, F.; Solomon, Marius M.; McHugh, T A; Wolf, Rudolf

doi:10.1016/s0022-5347(17)45914-3

Cited by 22 publications

(30 citation statements)

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“…27 Furthermore, attention was placed on the presence of hypoechogenic lesions in the prostate. The sonographic criteria for prostate cancer described by Lee et al 28 were used. If abnormalities were found, patients were sent to the urology outpatient clinic for further evaluation.…”

Section: Safetymentioning

confidence: 99%

Effect of Testosterone Supplementation on Functional Mobility, Cognition, and Other Parameters in Older Men

Emmelot-Vonk¹,

Verhaar²,

Pour³

et al. 2008

JAMA

447

323

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Section: Safetymentioning

confidence: 99%

Effect of Testosterone Supplementation on Functional Mobility, Cognition, and Other Parameters in Older Men

Emmelot-Vonk¹,

Verhaar²,

Pour³

et al. 2008

JAMA

447

323

View full text Add to dashboard Cite

“…However, it is clear that our experience is similar to other reports show ing that transrectal ultrasonography is a sensitive diag nostic method [4][5][6][7], A review of the literature suggests that many authors [6,[8][9][10][11][12][13] believed that prostatic cancer is relatively hyperechoic in relation to normal prostate or benign prostatic hyperplasia. Recently, however, Lee et al [14] reviewed the echograms of 33 patients with prostatic cancer and stressed that the echogenicity of prostatic cancer is basically hypoechoic and positive biopsy in the case with hyperechoic lesion may be due to cancer infil trating hyperplastic prostatic tissue.…”

Section: Diagnosis By Ultrasonographymentioning

confidence: 99%

Digital Examination and Transrectal Ultrasonography in the Diagnosis of Prostatic Cancer

Naito

Kimiya²,

Hasegawa³

et al. 1988

Eur Urol

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“…In 1985, Lee and co-workers [4], however, demonstrated that CaP in the peripheral zone has a predominantly hypoechoic ultrasound pattern. These findings were confirmed by other investigators [5,6].…”

Section: Introductionmentioning

confidence: 99%

Clinical Significance of the Echogenicity in Prostatic Ultrasound Findings in the Detection of Prostatic Carcinoma

Manseck¹,

Guhr²,

Hakenberg³

et al. 2000

Oncol Res Treat

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Background: Transrectal ultrasound is commonly performed in the clinical evaluation of the prostate. Ultrasound-guided randomized sextant biopsy became the standard procedure for the diagnosis of carcinoma of the prostate (CaP). A guided biopsy of sonographically irregular lesions of the prostate is not performed in randomized biopsies. An almost generally accepted opinion is that hypoechoic lesions are suspicious for the presence of CaP. However, the role of prostatic lesions with an echogenicity other than iso- or hypoechoic, e.g. hyperechoic or irregular lesions in relation to CaP is not clear. The intention of the present prospective study was to clarify the role of different prostatic ultrasound findings with a new-generation ultrasound probe in regard to their relevance concerning the presence of cancer. Material and Methods: 265 patients who were referred for prostatic evaluation because of an elevated PSA serum level or a positive digital rectal examination were enrolled in a prospective study. All patients had a systematic ultrasound-guided sextant biopsy of the prostate and a 4-core biopsy of the transition zone. All biopsy cores taken were guided by transrectal ultrasound. In case of a sonographically suspicious lesion, biopsy was always directed into this area. The predominant ultrasound appearance was separately recorded for each core. Results: Carcinoma of the prostate was detected in 87 (32.8%) of the 265 patients. Biopsy cores with isoechoic ultrasound findings revealed CaP in 7.6%. The data for hypoechoic, hyperechoic, mixed-echoic and anechoic lesions were 34.5, 26.9, 21.1 and 0%, respectively. Hypoechoic ultrasound findings were less frequently found in the transition zone of the prostate, but the rate of CaP detection was the same as in the peripheral zone of the prostate. Conclusions:The transrectal ultrasound pattern of the prostate yields important information about the presence of carcinoma of the prostate. Especially hypoechoic lesions indicate the presence of CaP in a significant proportion of cases. However, hyperechoic lesions and lesions of mixed or irregular echogenicity were found to contain cancer in significant numbers as well, and should therefore be considered to be suspicious for cancer when performing transrectal ultrasound of the prostate. Directed biopsy of irregular ultrasound patterns in the prostate seems therefore to be recommendable.

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Transrectal Ultrasound in the Diagnosis of Prostate Cancer: Location, Echogenicity, Histopathology, and Staging

Cited by 22 publications

References 0 publications

Effect of Testosterone Supplementation on Functional Mobility, Cognition, and Other Parameters in Older Men

Effect of Testosterone Supplementation on Functional Mobility, Cognition, and Other Parameters in Older Men

Digital Examination and Transrectal Ultrasonography in the Diagnosis of Prostatic Cancer

Clinical Significance of the Echogenicity in Prostatic Ultrasound Findings in the Detection of Prostatic Carcinoma

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