Transscleral Cyclophotocoagulation for the Treatment of Uncontrolled Glaucoma in a Boston Keratoprosthesis Type II Patient

Larrea, Begoña Arana; Črnej, Alja; Soto, Ana Arce; Andollo, Noelia; Ecenarro, Jaime Etxebarria

doi:10.1159/000522440

Cited by 3 publications

(1 citation statement)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a further complication, probably related to the keratoprosthesis surgery, two cyclophotocoagulations had to performed. The final visual acuity was 20/20 but the visual field revealed glaucoma related damage ( 196 ). OOKP and OKP are high risk procedures that are not commonly performed but might sometimes be the last resort to restore vision in selected patients.…”

Section: Surgical Management Of Complicationsmentioning

confidence: 99%

Challenges and concepts in the diagnosis and management of ocular graft-versus-host disease

Tappeiner

Heiligenhaus²,

Halter³

et al. 2023

Front. Med.

View full text Add to dashboard Cite

Graft-versus-host disease (GVHD) is characterized by tissue inflammation in the host following an allogeneic hematopoietic cell transplantation (HCT). The pathophysiology is complex and only incompletely understood yet. Donor lymphocyte interaction with the histocompatibility antigens of the host plays a crucial role in the pathogenesis of the disease. Inflammation may affect multiple organs and tissues, e.g., the gastrointestinal tract, liver, lung, fasciae, vaginal mucosa, and the eye. Subsequently, alloreactive donor-derived T and B lymphocytes may lead to severe inflammation of the ocular surface (i.e., cornea and conjunctiva) and the eyelids. Furthermore, fibrosis of the lacrimal gland may lead to severe dry eye. This review focuses on ocular GVHD (oGVHD) and provides an overview of current challenges and concepts in the diagnosis and management of oGVHD. Ophthalmic manifestations, diagnostic procedures, grading of severity and recommendations for ophthalmic examination intervals are provided. Management of ocular surface disease with lubricants, autologous serum eye drops, topical anti-inflammatory agents and systemic treatment options are described based on the current evidence. Ocular surface scarring and corneal perforation are severe complications of oGVHD. Therefore, ophthalmic screening and interdisciplinary treatment approaches are highly relevant to improve the quality of life of patients and to prevent potentially irreversible visual loss.

show abstract

Section: Surgical Management Of Complicationsmentioning

confidence: 99%

Challenges and concepts in the diagnosis and management of ocular graft-versus-host disease

Tappeiner

Heiligenhaus²,

Halter³

et al. 2023

Front. Med.

View full text Add to dashboard Cite

show abstract

Boston Type II Keratoprosthesis, 7 Years of Experience and Outcomes From a Spanish Tertiary Eye Care Hospital

Orive Bañuelos,

Sacristán Egüén,

Arce Soto

et al. 2025

American Journal of Ophthalmology

View full text Add to dashboard Cite

Micropulse laser cyclophotocoagulation in the treatment of secondary glaucoma in patients with post-burn and terminal dystrophic corneal leukoma as a stage of preparation for keratoprosthesis surgery

Sokolovskaya,

Golovin,

Starostina

et al. 2024

Glaucoma

View full text Add to dashboard Cite

PURPOSE. To evaluate the effectiveness of micropulse laser cyclophotocoagulation (mCPC) in patients with secondary glaucoma associated with post-burn and terminal dystrophic corneal leukomas.METHODS. Twelve patients (12 eyes) with corneal leukomas and secondary glaucoma underwent mCPC. The mean age of the patients was 44±6.5 years, including 8 men and 4 women. All patients exhibited elevated intraocular pressure (IOP), ranging from Tpalp "+" to Tpalp "++," despite being on maximum combination hypotensive therapy. Visual acuity for all patients was 1/∞ light perception with correct projection (proectia lucis certa).RESULTS. On the first postoperative day, IOP was reduced to Tpalp "+" in 4 patients and to Tpalp "N" in 8 patients. Hypotensive therapy was continued based on individual indications throughout the observation period. By day 7, IOP had decreased to Tpalp "N" in all patients and remained stable throughout the follow-up period. Visual acuity in all cases remained unchanged from the preoperative level. Ultrasound biomicroscopy (UBM) revealed that the mean ciliary body thickness (CBT) before surgery was 0.56±0.11 mm. On the first postoperative day, CBT increased by an average of 20.1% due to pronounced edema caused by hydration from the inflammatory response, with a gradual return to baseline by the 1-month follow-up. At 6 months, no statistically significant difference in CBT from the preoperative thickness was observed, with a mean CBT of 0.50±0.12 mm.CONCLUSIONS. Micropulse cyclophotocoagulation can be an effective treatment for secondary glaucoma in patients with post-burn and terminal dystrophic corneal leukomas. This technique reduces the risk of intraoperative and postoperative complications due to its non-invasive nature and low surgical trauma. The procedure can be repeated if IOP increases, and gentle laser parameters can help preserve visual potential.

show abstract

Transscleral Cyclophotocoagulation for the Treatment of Uncontrolled Glaucoma in a Boston Keratoprosthesis Type II Patient

Cited by 3 publications

References 18 publications

Challenges and concepts in the diagnosis and management of ocular graft-versus-host disease

Challenges and concepts in the diagnosis and management of ocular graft-versus-host disease

Boston Type II Keratoprosthesis, 7 Years of Experience and Outcomes From a Spanish Tertiary Eye Care Hospital

Micropulse laser cyclophotocoagulation in the treatment of secondary glaucoma in patients with post-burn and terminal dystrophic corneal leukoma as a stage of preparation for keratoprosthesis surgery

Contact Info

Product

Resources

About