Transsphenoidal Surgery of Nasal Liquorrhea as a Complication After Treatment of Prolactinomas  With Drugs

Polezhaev, A V; Cherebillo, V. Yu.; Свистов, Д В; Tsoy, U. A.; Voitsekhovsky, D. V.

doi:10.24884/0042-4625-2018-177-3-14-18

Cited by 2 publications

(1 citation statement)

References 9 publications

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“…Package of the operating area was carried out with the hemostatic absorbable material "Surgicel Fibrillar" [18]. The primary plastic of the cerebrospinal fluid fistula was found in 4 cases to be insolvent due to relapse of nasal liquorrhea after 1-2 weeks.…”

Section: Methodsmentioning

confidence: 99%

Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak

Karpishchenko¹,

Cherebillo²,

Vereshchagina³

et al. 2019

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Spontaneous nasal liquorrhea is a pathological condition associated with defects between the nasal cavity and the intracranial structures, which results in CSF leak from the nasal cavity. Diagnostic criteria include: anamnesis, examination of the nasal fluid, endoscopic examination of the nasal cavity, and CT-and MRI-cisternography. Conservative therapy is applicable to small fistulas. In the case of the inefficiency of this method, surgical method is then applied to the defect closure. Purpose of the study: To evaluate the effectiveness of endoscopic endonasal approach in the CSF leak treatment. Materials and methods: For the period from 2008 to 2018 at the Pavlov First Saint Petersburg State Medical University, at the clinic of neurosurgery of the Kirov Medical Institute and the Medical Research Center Almazov, 38 patients with spontaneous nasal liquorrhea were treated. All patients underwent plastic surgery of the CSF fistula by endoscopic endonasal approach. Results: In 4 cases, there was a large defect requiring secondary surgical intervention 1-2 weeks after the initial operation. Conclusions: The use of auto tissues (muscle or fat) is the method of choice for repeated surgical plastics of the cerebrospinal fluid fistula or in the case of a large size defect.

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Section: Methodsmentioning

confidence: 99%

Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak

Karpishchenko¹,

Cherebillo²,

Vereshchagina³

et al. 2019

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Transsphenoidal endoscopic appro ach in the treat ment of spontaneous cerebrospinal fluid (CSF) leak

Черебилло¹,

Karpishchenko²,

Puzakov³

et al. 2019

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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Introduction. Spontaneous nasal liquorrhea is a pathological condition associated with defect between nasal cavity and intracranial structures that lead to the expiration of the CSF from the nasal cavity.The objective is to evaluate the effectiveness of endoscopic endonasal approach in the CSF leak treatment.Material and methods. For the period from 2008 to 2018, 38 patients with spontaneous nasal liquorrhea were examined and treated in Pavlov First Saint Petersburg State Medical University, the clinic of neurosurgery of Kirov Medical Institute and Almazov National Medical Research Centre. All patients underwent plastic surgery of the CSF fistula by endoscopic endonasal aproach.Results. Only in 4 cases, there was a large defect, the failure of the closure of which required repeated surgical intervention in 1–2 weeks after the initial operation.Conclusion. The use of autologous tissues (muscle or fat autograft) is the method of choice for repeated surgical plastics of the cerebrospinal fluid fistula or in a large size defect (more than 5 mm).

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Transsphenoidal Surgery of Nasal Liquorrhea as a Complication After Treatment of Prolactinomas With Drugs

Cited by 2 publications

References 9 publications

Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak

Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak

Transsphenoidal endoscopic appro ach in the treat ment of spontaneous cerebrospinal fluid (CSF) leak

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