Transthoracic needle biopsy with a coaxially placed 20-gauge automated cutting needle: results in 122 patients.

Abstract

Coaxial TNB performed with an automated cutting needle helps provide a diagnosis in the majority of patients with focal chest disease and is particularly useful in the diagnosis of benign lesions.

Accuracy and sensitivity of computed tomography‐guided percutaneous needle biopsy of pulmonary hilar lymph nodes

“…The 93% accuracy rate with percutaneous hilar biopsies seen in this study is comparable to the accuracy rates reported with a combination of endobronchial ultrasound-and EUS-guided FNAB 14 and is at the upper end of the range for the accuracy rates reported for image-guided mediastinal biopsies (78%-94%) [8][9][10][11][12][13] and lung biopsies (88%-95%). [3][4][5][6][7]24,25 The diagnostic yield of endobronchial ultrasound may be increased by electromagnetic navigation techniques that allow biopsy of endobronchially invisible pulmonary lesions. 26 EUS-guided procedures allow only fine-needle aspiration of individual cells, which is usually sufficient for staging purposes.…”

“…1 Currently, the most important prognostic factor for localized lung cancer is metastatic involvement of the mediastinal and hilar lymph nodes. 2 Transthoracic percutaneous needle biopsy (PNB) is routinely used to diagnose parenchymal [3][4][5][6][7] and accessible mediastinal [8][9][10][11][12][13] neoplasms.…”

Diagnostic imaging of lung cancer

“…CT affords good visualization of all thoracic structures and CT guided biopsy has an accuracy for diagnosing malignancy of 80-95% [131,132]. It is the procedure of choice for sampling peripheral nodules (v2 cm in diameter) as the yield for transbronchial needle biopsy, in the absence of an endobronchial lesion, falls from 92-95% to 50-80% [132].…”

“…It is the procedure of choice for sampling peripheral nodules (v2 cm in diameter) as the yield for transbronchial needle biopsy, in the absence of an endobronchial lesion, falls from 92-95% to 50-80% [132]. FNA is the preferred sampling method of parenchymal nodules in order to reduce the incidence of complications and is known to have a similar sensitivity in detecting malignancy as core biopsy [131]. However, small tissue fragments for histological evaluation can generally be obtained with 19-22 gauge needles in 40-75% of patients [132].…”

“…However, small tissue fragments for histological evaluation can generally be obtained with 19-22 gauge needles in 40-75% of patients [132]. Such evaluation is valuable because it lends confidence to a cytological diagnosis of cancer, to cell-type determination and to the reliability of a negative result [131,132]. When a cavitatory or necrotic lesion is encountered, sampling of the wall is recommended to obtain viable tumour material.…”