Transvaginal color Doppler study of middle cerebral artery blood flow in early normal and abnormal pregnancy

Kurjak, Asım; Predanić, Mladen; Kupesic-Urek, Sanja; Funduk-Kurjak, Biserka; Demarin, Vida; Salihagić, Aida

doi:10.1046/j.1469-0705.1992.02060424.x

Cited by 28 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Few studies have addressed this issue. Kurjak et al [ 15] found that Doppler studies of the middle cerebral artery in early pregnancy were unlikely to be of value in identifying fetal hemodynamic disorders in the early stages of spontaneous abortion. More recently,…”

Section: Discussionmentioning

confidence: 99%

Transvaginal Color Doppler Assessment of Fetal Circulation in Normal Early Pregnancy

Alcázar

Rovira²,

Ruiz-Perez³

et al. 1997

Fetal Diagn Ther

View full text Add to dashboard Cite

A prospective cross-sectional study was performed in 81 consecutive patients with low-risk singleton pregnancies and gestational age from 9 to 12 weeks of gestation in order to assess the fetal circulation at this stage of pregnancy. Patients’ mean age was 29.8 ± 3.8 (SD) years. Mean gestational age was 10.5 ± 1.1 weeks. All patients underwent transvaginal color velocity imaging and pulsed Doppler ultrasound to obtain the blood flow velocity waveforms (FVWs) from three fetal vessels: umbilical artery, abdominal aorta, and intracranial vessels. The peak systolic velocity (PSV) and pulsatility index (PI) were analyzed. Optimal FVWs from each vessel were obtained in 98.8, 75.3 and 91.3% of fetuses, respectively. Linear regression analysis showed a significant progressive increase in PSV in the umbilical artery (r = 0.49, p < 0.0001) and intracranial vessels (r = 0.36, p = 0.018) simultaneous to a significant decrease in PI in both vessels (umbilical artery r = ––0.37, p = 0.0007; intracranial vessels r = ––0.56, p < 0.0001). No significant change was noted in the abdominal aorta in PSV (r = 0.06, p > 0.05) or in PI (r = ––0.15, p > 0.05).

show abstract

Section: Discussionmentioning

confidence: 99%

Transvaginal Color Doppler Assessment of Fetal Circulation in Normal Early Pregnancy

Alcázar

Rovira²,

Ruiz-Perez³

et al. 1997

Fetal Diagn Ther

View full text Add to dashboard Cite

show abstract

“…The middle cerebral artery, as the terminal branch of the internal carotid artery, has been visualized at the base of the fetal brain [12] from the 8th to 11th gestational week as well as at the level of the heart-shaped cerebral peduncles at its lateral-anteral borders, running anterolaterally towards the lateral edge o f the orbit (from the 11th to 16th gestational week). When blood flow was obtained, pulsed Doppler sample volume was focused on it and the resistance index (RI) was calculated in the uteroplacental arteries, while in fetal vessels the pulsatility index (PI) was measured.…”

Section: Methodsmentioning

confidence: 99%

Assessment of the Fetomaternal Circulation in Threatened Abortion by Transvaginal Color Doppler

et al. 1994

View full text Add to dashboard Cite

Transvaginal color Doppler was used to investigate blood flow in the fetomaternal circulation of 60 women with threatened abortion and 90 women with normal intrauterine pregnancy. The obtained Doppler sonograms were analyzed and the resistance index (RI) was calculated in the maternal circulation, while in the fetal circulation the pulsatility index (PI) was used. There was no significant difference in the RI values of the maternal circulation between women with normal pregnancies and pregnancies complicated by bleeding, but with normal pregnancy outcome (p > 0.05). No differences in RI values of the uterine, arcuate and radial arteries were found between pregnancies with threatened abortion and normal pregnancy outcome and women with abnormal outcome (p > 0.05). In 9 of 21 women with visible retrochorionic hematoma, the RI of the spiral arteries was higher on the hematoma side in comparison to the opposite side (p < 0.01). This could be a consequence of the mechanical compression caused by the hematoma. In 3 of 4 cases of missed abortion, the RI of the spiral arteries was lower in comparison to the control group. Such findings could be caused by the vasodilatating products of inflammation which probably exist in such areas. There was no significant difference in terms of the PI of fetal blood vessels between normal pregnancy and threatened abortions with normal outcome, as well as between threatened abortions with normal outcome and subsequent abortions of live fetuses (p > 0.05).

show abstract

“…In a study by Kurjak et al [30] using transvaginal ultrasound, the visualization rate of pulsation on the base of the skull increased from 50% at the 8th gestational week to 83% at the 10th week. From the 11th week onwards it became a constant finding.…”

Section: Cerebral Arterial Doppler Waveforms In Normal Fetusesmentioning

confidence: 98%

Fetal Cerebrovascular Circulation: A Review of Prenatal Ultrasound Assessment

Degani¹

2008

Gynecol Obstet Invest

View full text Add to dashboard Cite

Antenatal intrauterine cerebrovascular events were found to play an important role in the pathogenesis of perinatal brain damage. Changes in placental vascular resistance, cardiac contractibility, vessel compliance, and blood viscosity alter the normal dynamics of fetal cerebral circulation. The circulatory mechanisms described in animal fetuses also operate in the human fetus. The isthmus of the aorta represents a watershed area reflecting the redistribution of blood during increased peripheral resistance and hypoxia. The fetal cerebrovascular system acts locally within the skull and interacts with the other components of fetal circulation to compensate by redistribution of blood in case of shortage in resources. The introduction of various sonographic techniques and the collection of data from the arterial and venous cerebral circulation have improved our understanding of the regulatory mechanisms involved in fetal cerebral hemodynamic events. Anatomical and physiological considerations of cerebral vasculature in health and disease are relevant in the research of variations in fetal brain blood perfusion. Changes in flow characteristics in fetal cerebral vasculature can be used for clinical decisions. However, caution is advised before applying research data into practice. The clinical utility is well established in situations of fetal compromise such as growth restriction and anemia.

show abstract

Transvaginal color Doppler study of middle cerebral artery blood flow in early normal and abnormal pregnancy

Cited by 28 publications

References 0 publications

Transvaginal Color Doppler Assessment of Fetal Circulation in Normal Early Pregnancy

Transvaginal Color Doppler Assessment of Fetal Circulation in Normal Early Pregnancy

Assessment of the Fetomaternal Circulation in Threatened Abortion by Transvaginal Color Doppler

Fetal Cerebrovascular Circulation: A Review of Prenatal Ultrasound Assessment

Contact Info

Product

Resources

About