Transverse erythronychia: A unique nail manifestation of COVID-19 infection and brief review of COVID-19 associated nail changes

Sil, Abheek; Ghosh, Sue; Das, Anupam; Chandra, Atanu

doi:10.1177/14782715221142559

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…Skin changes resulting from COVID-19 also affect the nails. These are rare changes that occur in patients of all ages, regardless of their origin [104,105]. As a result of infection with the SARS-CoV-2 virus, the following have been reported: the following changes on the nails: a red crescent sign, Mees' lines, Beau's lines [106][107][108].…”

Section: Nail Changesmentioning

confidence: 99%

“…The red crescent symptom was also reported two days after the onset of symptoms of the SARS-CoV-2 infection [ 107 ]. Most likely, this symptom occurs as a result of an immune reaction resulting from COVID-19 directed at the capillaries of the nail bed [ 105 , 106 , 109 ]. One study conducted on 55 patients indicated that the red crescent symptom occurred in 32.5% of patients (fingernails) and in 2.3% of patients (toe nails) [ 104 ].…”

Section: Introductionmentioning

confidence: 99%

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The most common skin symptoms in young adults and adults related to SARS-CoV-2 virus infection

Zaborska,

Chruszcz,

Sadowski

et al. 2024

Arch Dermatol Res

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Scientists from various areas of the world indicate in their studies that skin lesions occur in the course of infection with the SARS-CoV-2 virus. This article is a review of the most frequently described cutaneous manifestations of SARS-CoV-2 virus infection and the potential pathophysiology of their development, as well as information on abnormalities in histopathological tests. The article describes the impact of some factors related to the COVID-19 pandemic on the exacerbation of chronic dermatological diseases. This work was constructed on the basis of 142 research studies, reviews, and meta-analyses, focusing on the methods and materials used in individual works as well as the results and conclusions resulting from them. Some skin lesions may be a potential prognostic marker of the course of the disease and may also be a prodromal symptom or the only symptom of SARS-CoV-2 virus infection. Stress related to the COVID-19 pandemic may exacerbate some chronic dermatological diseases. A correlation was observed between the type of skin lesions and the patient’s age. The occurrence of skin diseases may also be influenced by drugs used to treat infections caused by SARS-CoV-2. A relationship was observed between the patient’s ethnic origin and skin lesions occurring in the course of COVID-19. There is a need to further diagnose the cutaneous manifestations of SARS-CoV-2 infection and to learn the detailed pathomechanism of their occurrence in order to better understand the essence of the disease and find an appropriate treatment method.

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Section: Nail Changesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The most common skin symptoms in young adults and adults related to SARS-CoV-2 virus infection

Zaborska,

Chruszcz,

Sadowski

et al. 2024

Arch Dermatol Res

View full text Add to dashboard Cite

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Nail Disorders in Patients Living with HIV Coinfected with Monkeypox: A Clinical Study in 69 Mexican Cases

Sánchez-Cárdenas,

Silva Flores,

Mendoza Ibarra

et al. 2024

Skin Appendage Disord

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Introduction: Several infectious diseases can present nail manifestations, which may be useful for diagnosis and prognosis, and only a few reports have been made regarding monkeypox (mpox). The objective of this study was to describe the clinical characteristics of nail alterations in patients living with HIV coinfected with mpox. Methods: A prospective, cross-sectional study included patients living with HIV/AIDS, coinfected with mpox. We examined all 20 nails in search of nail plate alterations. Patients were divided into two groups, with and without nail disease, and the CD4 count was noted according to the Centers for Disease Control and Prevention (CDC) classification. A χ2 or Fisher’s exact test for qualitative variables and Mann-Whitney U and Kruskal-Wallis tests with post hoc Bonferroni test for quantitative variables were used to compare them. Data were analyzed with the SPSS Statistics 25 software. Results: Sixty-nine patients were included. The frequency of nail involvement was 58%. Papulonodular lesions were the most frequent type identified, with 21 cases (30.4%). A significant difference was observed between patients with nail disease versus median CD4 count (160 vs. 700/mm3; p = 0.002) and median HIV viral load (45,000 vs. 900/mL; p = 0.009). When comparing the characteristics of the nail lesions with the CDC Classification System for HIV infection by the CD4 count, a significant difference was observed in foot involvement, splinter hemorrhages, papulo-nodular lesions, anonychia, onychomadesis, acute paronychia, and nail bed ulcer-atrophy (p < 0.05). Conclusions: The frequency of nail lesions is high in patients living with HIV coinfected with mpox. In addition, they tend to be more destructive in patients with lower CD4 counts and higher viral loads.

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Transverse erythronychia: A unique nail manifestation of COVID-19 infection and brief review of COVID-19 associated nail changes

Cited by 2 publications

References 12 publications

The most common skin symptoms in young adults and adults related to SARS-CoV-2 virus infection

The most common skin symptoms in young adults and adults related to SARS-CoV-2 virus infection

Nail Disorders in Patients Living with HIV Coinfected with Monkeypox: A Clinical Study in 69 Mexican Cases

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