Tratamento cirúrgico da aorta ascendente e arco com perfusão cerebral anterógrada e hipotermia moderada

Martins, Marcelo Sávio da Silva; Sá, Mauro Paes Leme de; Abad, Leonardo; Bastos, Eduardo Sérgio; Franklin, Ney; Baptista, Alvaro Luiz Xavier de B. M.; Annibal, Jorge Viana; Bezerra, Alvaro Barde

doi:10.1590/s0102-76382006000400017

Cited by 2 publications

(2 citation statements)

References 20 publications

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“…Several prospective studies of selective cerebral perfusion, with demonstrated efficacy in the prevention of neurological sequelae [18,19], and reviews about intraoperative neuroprotection, particularly during CPB do not emphasize the brain monitoring as a means of evaluating the quality of neuroprotection in real or capable time [20,21]. Certainly this is due to the unavailability in the domestic market and high cost of brain monitors, however, as frequent measurement of SjO 2 may be feasible and useful.…”

Section: Discussionmentioning

confidence: 99%

Correlação entre a SvO2 e SjO2 durante a cirurgia cardíaca com circulação extracorpórea em crianças

Klamt¹,

Nabarro²,

Vicente³

et al. 2011

Rev Bras Cir Cardiovasc

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Section: Discussionmentioning

confidence: 99%

Correlação entre a SvO2 e SjO2 durante a cirurgia cardíaca com circulação extracorpórea em crianças

Klamt¹,

Nabarro²,

Vicente³

et al. 2011

Rev Bras Cir Cardiovasc

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“…The use of well-known, commercially available, non-degradable synthetic grafts such as expanded polytetrafluoroethylene (e-PTFE*) and polyethylene terephthalate (PET*) for large arterial reconstructions such as that of the aorta, arch vessels, and common femoral artery, where there are high flow and low resistance, has shown success in clinical trials. 52,80,122,170 Although graft infection (< 3%), 146 dilation (35%), 72 and occlusion (2%) 72 remain challenging problems for a small number of patients who have undergone procedures using these grafts, the majority of patients can expect permanent patency and minimal need for repeated procedures. 114,138 A recent study showed that the use of e-PTFE* in the bypass procedure had patency of 39% at 5 years.…”

Section: Introductionmentioning

confidence: 99%

Considerations in the Development of Small-Diameter Vascular Graft as an Alternative for Bypass and Reconstructive Surgeries: A Review

Obiweluozor

Emechebe

Kim

et al. 2020

Cardiovasc Eng Tech

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Background-Current design strategies for small diameter vascular grafts (< 6 mm internal diameter; ID) are focused on mimicking native vascular tissue because the commercially available grafts still fail at small diameters, notably due to development of intimal hyperplasia and thrombosis. To overcome these challenges, various design approaches, material selection, and surface modification strategies have been employed to improve the patency of small-diameter grafts. Review-The purpose of this review is to outline various considerations in the development of small-diameter vascular grafts, including material choice, surface modifications to enhance biocompatibility/endothelialization, and mechanical properties of the graft, that are currently being implanted. Additionally, we have taken into account the general vascular physiology, tissue engineering approaches, and collective achievements of the authors in this area. We reviewed both commercially available synthetic grafts (e-PTFE and PET), elastic polymers such as polyurethane and biodegradable and bioresorbable materials. We included naturally occurring materials by focusing on their potential application in the development of future vascular alternatives. Conclusion-Until now, there are few comprehensive reviews regarding considerations in the design of small-diameter vascular grafts in the literature. Here-in, we have discussed in-depth the various strategies employed to generate engineered vascular graft due to their high demand for vascular surgeries. While some TEVG design strategies have shown greater potential in contrast to autologous or synthetic ePTFE conduits, many are still hindered by high production cost which prevents their widespread adoption. Nonetheless, as tissue engineers continue to develop on their strategies and procedures for improved TEVGs, soon, a reliable engineered graft will be available in the market. Hence, we anticipate a viable TEVG with resorbable property, fabricated via electrospinning approach to hold a greater potential that can overcome the challenges observed in both autologous and allogenic grafts. This is because they can be mechanically tuned, incorporated/surface-functionalized with bioactive molecules and mass-manufactured in a reproducible manner. It is also found that most of the success in engineered vascular graft approaching commercialization is for large vessels rather than small-diameter grafts used as cardiovascular bypass grafts. Consequently, the field of vascular engineering is still available for future innovators that can take up the challenge to create a functional arterial substitute.

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Tratamento cirúrgico da aorta ascendente e arco com perfusão cerebral anterógrada e hipotermia moderada

Cited by 2 publications

References 20 publications

Correlação entre a SvO<sub>2</sub> e SjO<sub>2</sub> durante a cirurgia cardíaca com circulação extracorpórea em crianças

Correlação entre a SvO<sub>2</sub> e SjO<sub>2</sub> durante a cirurgia cardíaca com circulação extracorpórea em crianças

Considerations in the Development of Small-Diameter Vascular Graft as an Alternative for Bypass and Reconstructive Surgeries: A Review

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