Tratamiento del síndrome de Kounis

Canosa, Michele; Orjales, M.J. Castro; Fariñas, Fernando; Jiménez, A. García; Cortés, Javier Martínez

doi:10.1016/j.medin.2011.01.010

Cited by 12 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Regarding the ECG in KS, the most common finding is ST segment elevation in anterior and inferior leads, but it may show normal or nonspecific results. The right coronary artery is the most frequently affected by vasospasm, although the reason is unknown [ 7 , 50 ]. In cases of vasospasm, ST elevation is characterized by being transient (Fig.…”

Section: Diagnosismentioning

confidence: 99%

“…Adrenaline is the treatment of choice in anaphylaxis, and it must also be administered early because it prolongs survival. However, in the presence of acute coronary syndrome, it can aggravate ischemia, prolong the QT interval, and induce coronary vasospasm and arrhythmias, especially in older and hypertensive patients [ 50 ]. As a further complication, an adrenaline-induced myocardial infarction can also occur [ 21 •].…”

Section: Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Drug-Induced Kounis Syndrome: Latest Novelties

Ollo-Morales,

Gutierrez-Niso,

De-la-Viuda-Camino

et al. 2023

Curr Treat Options Allergy

View full text Add to dashboard Cite

Opinion statement Kounis syndrome (KS) is defined by an acute coronary syndrome associated with hypersensitivity reactions, an under-diagnosed life-threatening medical emergency. Although multiple causes have been described, drugs constitute the most frequent cause. The purpose of this review is to update knowledge about drug-induced KS, to give guidelines on the correct diagnosis and treatment. This article reviews the literature on drug-induced KS from the last 5 years. Antibiotics and NSAIDs are the most frequently implicated drugs. In addition, data on pathophysiology, clinical presentation, diagnosis, and management are reviewed in detail. Highlight that there is a great deal of variability in the diagnosis and especially in the treatment of KS. This review provides a valuable selection of practical resources for all stakeholders to support effective care for KS, from a cardiologic and allergologic point of view. Future research should focus on developing validated, evidence-based, and patient-centered tools to improve the management of KS.

show abstract

Section: Diagnosismentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

Drug-Induced Kounis Syndrome: Latest Novelties

Ollo-Morales,

Gutierrez-Niso,

De-la-Viuda-Camino

et al. 2023

Curr Treat Options Allergy

View full text Add to dashboard Cite

show abstract

Complicações cardíacas em síndrome de Kounis tipo I induzida por metamizol

Juste

Garcés

Enguita

et al. 2016

Brazilian Journal of Anesthesiology

View full text Add to dashboard Cite

Kounis syndrome is defined as the coincidental occurrence of allergic reaction and acute coronary syndrome secondary to vasospasm. Anti-inflammatory drugs are included as one of the multiple causes. Current data available about this syndrome come from case reports. We present the case of a patient who suffered Kounis syndrome with cardiogenic shock and asystole after intravenous infusion of Metamizole, and in which no lesions were observed in coronariography.

show abstract