Trauma histories of non-treatment-seeking prescription opioid-dependent individuals

McCauley, Jenna L.; Mercer, Mary Ashley; Brady, Kathleen T.; Back, Sudie E.

doi:10.1016/j.drugalcdep.2014.02.396

Cited by 2 publications

(3 citation statements)

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“…Providing comprehensive interventions that address both substance use, PTSD symptoms, and improved emotion regulation strategies may prove beneficial. Although such treatments exist (Mills et al, 2004), there is need for dissemination given the high rate of trauma exposure among those who regularly use opioids (McCauley et al, 2014). …”

Section: Discussionmentioning

confidence: 99%

The intervening role of urgency on the association between childhood maltreatment, PTSD, and substance-related problems

Mirhashem

Allen

Adams

et al. 2017

Addictive Behaviors

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A range of risk factors lead to opioid use and substance-related problems (SRP) including childhood maltreatment, elevated impulsivity, and psychopathology. These constructs are highly interrelated such that childhood maltreatment is associated with elevated impulsivity and traumarelated psychopathology such as posttraumatic stress disorder (PTSD), and impulsivity—particularly urgency—and PTSD are related. Prior work has examined the association between these constructs and substance-related problems independently and it is unclear how these multifaceted constructs (i.e., maltreatment types and positive and negative urgency) are associated with one another and SRP. The current study used structural equation modeling (SEM) to examine the relations among childhood maltreatment, trait urgency, PTSD symptoms, and SRP in a sample of individuals with a history of opioid use. An initial model that included paths from each type of childhood maltreatment, positive and negative urgency, PTSD and SRP did not fit the data well. A pruned model with excellent fit was identified that suggested emotional abuse, positive urgency, and negative urgency were directly related to PTSD symptoms and only PTSD symptoms were directly related to SRP. Furthermore, significant indirect effects suggested that emotional abuse and negative urgency were related to SRP via PTSD symptom severity. These results suggest that PTSD plays an important role in the severity of SRP.

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Section: Discussionmentioning

confidence: 99%

The intervening role of urgency on the association between childhood maltreatment, PTSD, and substance-related problems

Mirhashem

Allen

Adams

et al. 2017

Addictive Behaviors

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“…One study conducted with OUD patients found that they reported higher pain levels than participants in a control group (Ives et al, 2006). This is important because patients are often introduced to opioids for pain after a medical procedure (Ives et al, 2006) and extended use may result in development of both tolerance and physical dependence on the substance (Ives et al, 2006;Edlund et al, 2007;McCauley, Mercer, Brady, & Back, 2014). The longer a patient has been using opioids, the more likely he or she is to develop a use disorder (Edlund et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

“…Various studies have shown that the presence of emotional and physical abuse are the strongest predictors of developing a SUD, especially in men (Mirhashem, et al, 2017). Notably, while the experience of traumatic events in an individual's life can make him or her more susceptible to developing any SUD (Boscarino et al, 2010;McCauley et al, 2014), prescription opioid use, specifically, has been associated with higher scores on inventories measuring PTSD symptoms (Meier, Lambert-Harris, McGovern, Xie, & McLeman, 2014 Further, though trauma can occur at any point during a patient's life, the most marked effects are shown when traumatic events occur during childhood (Conroy et al, 2009;Dube et al, 2013;Heffernan et al, 2000;Barahmand, Khazaee, & Hashjin, 2016). In addition to any type of abuse a child might experience, parental separation, parental conflict, and parental substance abuse exponentially increase the rates of developing a SUD in the future (Conroy et al, 2009;Barahmand et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Factors Associated with Opioid Use Disorder Diagnosis and Treatment Progress

Mathai

2019

UFJUR

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Previous research has shown that various environmental aspects, such as a history of abuse, trauma, and pain can influence the incidence of opioid use disorder (OUD). The aims of this study were to determine risk factors associated specifically with opioid use disorder, and to identify factors that may predict treatment progress for opioid use disorder patients. Three-hundred six patients from an abstinence-based residential treatment center participated in this study. Participants completed a comprehensive battery, which included measures assessing quality of life, craving, abstinence self-efficacy, adverse childhood experiences, trauma exposure, and physical pain symptoms at treatment intake and again after 28 days of treatment. Independent t-test results showed significant differences between patients with and without opioid use disorders in social relationships, confidence abstaining from alcohol and drugs, pain intensity, and drug craving. Multiple regression analyses demonstrated that presence of an opioid use disorder predicted alcohol abstinence, social relationships, and baseline environment. Results revealed shifting attitudes towards substance use and social relationships during the opioid group’s time in treatment. Cravings and urges were identified as important focuses for future treatment of opioid use disorder. Hyperalgesia was seen as an effect of extended opioid use and its impact decreased through drug abstinence. Limitations included a small sample size, a large proportion of wealthy individuals, and age differences between the two groups.

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Trauma histories of non-treatment-seeking prescription opioid-dependent individuals

Cited by 2 publications

References 0 publications

The intervening role of urgency on the association between childhood maltreatment, PTSD, and substance-related problems

The intervening role of urgency on the association between childhood maltreatment, PTSD, and substance-related problems

Factors Associated with Opioid Use Disorder Diagnosis and Treatment Progress

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