2019
DOI: 10.1111/jth.14571
|View full text |Cite
|
Sign up to set email alerts
|

Trauma‐induced coagulopathy: The past, present, and future: A comment

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
3
0

Year Published

2021
2021
2024
2024

Publication Types

Select...
4
1

Relationship

2
3

Authors

Journals

citations
Cited by 5 publications
(3 citation statements)
references
References 10 publications
0
3
0
Order By: Relevance
“…Massive thrombin generation due to the activation of coagulation may lead to the consumption of anticoagulant factors, such as antithrombin and protein C, followed by further activation of coagulation. These changes contribute to hypercoagulability inside the vessels, leading to intravascular microthrombosis in the brain and other organs, and hypocoagulability outside the vessels due to consumptive coagulopathy, leading to the progression of intracranial hemorrhage ( 34 ).…”
Section: Discussionmentioning
confidence: 99%
“…Massive thrombin generation due to the activation of coagulation may lead to the consumption of anticoagulant factors, such as antithrombin and protein C, followed by further activation of coagulation. These changes contribute to hypercoagulability inside the vessels, leading to intravascular microthrombosis in the brain and other organs, and hypocoagulability outside the vessels due to consumptive coagulopathy, leading to the progression of intracranial hemorrhage ( 34 ).…”
Section: Discussionmentioning
confidence: 99%
“…The SA/GO/MBG composite aerogels were soaked in tris-HCl solution (pH 7.4) at 37 °C for different time periods to test the release of ions. The ratio of the solution volume to the aerogel volume was 20 mL/cm 3 average value. After 1, 3, 7, and 14 days of soaking, the tris-HCl solutions were refreshed and collected at every time period.…”
Section: Methodsmentioning
confidence: 99%
“…Emergency trauma caused by various accidents increases the risk of massive hemorrhage and infection, which is even life-threatening. As reported, deaths of hemorrhagic shock after excessive bleeding account for 30–40% of all deaths due to trauma. Hence, instant hemostasis in trauma is significant to save lives. Besides, the protective barriers of the human body such as the skin and mucosa are severely damaged after trauma, which makes the wound easier to be infected by bacteria.…”
Section: Introductionmentioning
confidence: 99%