Traumatic Injuries

Bhatia, Sujata K.

doi:10.1007/978-1-4419-6920-0_10

Cited by 9 publications

(5 citation statements)

References 192 publications

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“…And it is proven that they are non-toxic, non-carcinogenic, and have good histocompatibility and significant hemostasis. It was reported that the Omnex ® consisting of n-octyl α-cyanoacrylate and butyl lactoyl-2cyanoacrylate could stop bleeding (Bhatia 2010). In addition, the Glubran ® and Glubran2 ® , which are made of n-Butyl-2cyanoacrylate and methacryloxysulpholane, have bacteriostatic and hemostatic properties (Montanaro, Arciola et al, 2000).…”

Section: Poly(cyanoacrylates)mentioning

confidence: 99%

Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative Medicine, Volume II

2024

Frontiers Research Topics

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Frontiers is more than just an open access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge. Frontiers provides immediate and permanent online open access to all its publications, but this alone is not enough to realize our grand goals. Frontiers journal seriesThe Frontiers journal series is a multi-tier and interdisciplinary set of openaccess, online journals, promising a paradigm shift from the current review, selection and dissemination processes in academic publishing. All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service to the scholarly community. At the same time, the Frontiers journal series operates on a revolutionary invention, the tiered publishing system, initially addressing specific communities of scholars, and gradually climbing up to broader public understanding, thus serving the interests of the lay society, too. Dedication to qualityEach Frontiers article is a landmark of the highest quality, thanks to genuinely collaborative interactions between authors and review editors, who include some of the world's best academicians. Research must be certified by peers before entering a stream of knowledge that may eventually reach the public -and shape society; therefore, Frontiers only applies the most rigorous and unbiased reviews. Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new generation. What are Frontiers Research Topics?Frontiers Research Topics are very popular trademarks of the Frontiers journals series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area.

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Section: Poly(cyanoacrylates)mentioning

confidence: 99%

Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative Medicine, Volume II

2024

Frontiers Research Topics

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“…And it is proven that they are non-toxic, non-carcinogenic, and have good histocompatibility and significant hemostasis. It was reported that the Omnex ® consisting of n-octyl α-cyanoacrylate and butyl lactoyl-2-cyanoacrylate could stop bleeding ( Bhatia 2010 ). In addition, the Glubran ® and Glubran2 ® , which are made of n-Butyl-2-cyanoacrylate and methacryloxysulpholane, have bacteriostatic and hemostatic properties ( Montanaro, Arciola et al, 2000 ).…”

Section: The Characteristic and Application Of The Various Hemostatic...mentioning

confidence: 99%

Advances in the development and optimization strategies of the hemostatic biomaterials

Guo

Cheng

Sun

et al. 2023

Front. Bioeng. Biotechnol.

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Most injuries are accompanied by acute bleeding. Hemostasis is necessary to relieve pain and reduce mortality in these accidents. In recent years, the traditional hemostatic materials, including inorganic, protein-based, polysaccharide-based and synthetic materials have been widely used in the clinic. The most prominent of these are biodegradable collagen sponges (Helistat®, United States), gelatin sponges (Ethicon®, SURGIFOAM®, United States), chitosan (AllaQuixTM, ChitoSAMTM, United States), cellulose (Tabotamp®, SURGICEL®, United States), and the newly investigated extracellular matrix gels, etc. Although these materials have excellent hemostatic properties, they also have their advantages and disadvantages. In this review, the performance characteristics, hemostatic effects, applications and hemostatic mechanisms of various biomaterials mentioned above are presented, followed by several strategies to improve hemostasis, including modification of single materials, blending of multiple materials, design of self-assembled peptides and their hybrid materials. Finally, the exploration of more novel hemostatic biomaterials and relative coagulation mechanisms will be essential for future research on hemostatic methods.

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“…Although some cyanoacrylate tissue adhesives are approved by FDA and commercially used for the closure of a local skin incision and barrier of a microbial penetration, they remain the inflammatory responses that may inhibit the collagen reconstruction and wound repair ( Montanaro et al, 2001 ; Singer et al, 2008 ; Bhatia, 2010 ).…”

Section: Synthetic Polymers-based Hemostatic Adhesivesmentioning

confidence: 99%

Recent Advances on Synthetic and Polysaccharide Adhesives for Biological Hemostatic Applications

Chen

Wang

et al. 2020

Front. Bioeng. Biotechnol.

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Rapid hemostasis and formation of stable blood clots are very important to prevent massive blood loss from the excessive bleeding for living body, but their own clotting process cannot be completed in time for effective hemostasis without the help of hemostatic materials. In general, traditionally suturing and stapling techniques for wound closure are prone to cause the additional damages to the tissues, activated inflammatory responses, short usage periods and inevitable second operations in clinical applications. Especially for the large wounds that require the urgent closure of fluids or gases, these conventional closure methods are far from enough. To address these problems, various tissue adhesives, sealants and hemostatic materials are placed great expectation. In this review, we focused on the development of two main categories of tissue adhesive materials: synthetic polymeric adhesives and naturally derived polysaccharide adhesives. Research of the high performance of hemostatic adhesives with strong adhesion, better biocompatibility, easy usability and cheap price is highly demanded for both scientists and clinicians, and this review is also intended to provide a comprehensive summarization and inspiration for pursuit of more advanced hemostatic adhesives for biological fields.

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Traumatic Injuries

Cited by 9 publications

References 192 publications

Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative Medicine, Volume II

Bioengineering and Biotechnology Approaches in Cardiovascular Regenerative Medicine, Volume II

Advances in the development and optimization strategies of the hemostatic biomaterials

Recent Advances on Synthetic and Polysaccharide Adhesives for Biological Hemostatic Applications

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