Traumatic Vestibular Diseases

Mygind, S. H.

doi:10.3109/00016481809122011

Cited by 14 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vestibular dysfunction has long been recognized as one of the possible consequences of head injury. 9-12 Balance problems are among the most commonly reported chronic symptoms after a mild head injury (concussion), with incidence ranging from 24% to 83%. 13-15 Posttraumatic dizziness was also demonstrated to result in poorer quality of life, 16,17 performance of activities of daily living, 18 self-perception of disability, 19 and psychological well-being.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Peripheral Vestibular System Histopathologic Changes following Head Injury without Temporal Bone Fracture

Knoll¹,

Ishai²,

Trakimas

et al. 2018

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

Objective. Vestibular symptoms such as dizziness and vertigo are common after head injury and may be due to trauma to the peripheral vestibular system. The pathophysiology of peripheral vestibular symptoms following head injury without temporal bone (TB) fracture, however, is not well understood. Herein, we investigate the histopathology of the peripheral vestibular system of patients who sustained head injury without a TB fracture. Study Design. Otopathology study. Setting. Otopathology laboratory. Subjects and Methods. TB of subjects with a history of head injury without TB fractures were included and evaluated by light microscopy. Specimens were assessed for qualitative and quantitative characteristics, such as number of Scarpa's ganglion cells in the superior and inferior vestibular nerves, vestibular hair cell and/or dendrite degeneration in vestibular end organs, presence of vestibular hydrops, and obstruction of the endolymphatic duct. Results. Five cases (n = 5 TBs) had evidence of vestibular pathology. There was a decrease of 48.6% (range, 40%-59%) in the mean count of Scarpa's ganglion cells as compared with that of normative historical age-matched controls. Moderate to severe degeneration of the vestibular membranous labyrinth was identified in the posterior, superior, and lateral canals in several cases (50%, n = 4 TBs). The maculae utriculi and sacculi showed mild to severe degeneration in 2 cases. Additional findings include vestibular hydrops (25%, n = 2 TBs) and blockage of the endolymphatic duct (n = 1 TB). Conclusions. Otopathologic analysis of patients with a history of head injury without TB fracture demonstrated peripheral vestibular otopathology. Future studies are necessary to determine if otopathology findings are directly attributable to head injury.

show abstract

mentioning

confidence: 99%

“…Vestibular dysfunction has long been recognized as one of the possible consequences of head injury 9‐12 . Balance problems are among the most commonly reported chronic symptoms after a mild head injury (concussion), with incidence ranging from 24% to 83% 13‐15 .…”

mentioning

confidence: 99%

Peripheral Vestibular System Histopathologic Changes following Head Injury without Temporal Bone Fracture

Knoll¹,

Ishai²,

Trakimas

et al. 2018

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

“…Vestibular symptoms have long been recognized as a consequence of head injury . Balance problems are among the most commonly reported chronic symptoms after mild head injury, such as a concussion, with an incidence ranging from 24% to 83% .…”

Section: Introductionmentioning

confidence: 99%

“…11 Vestibular symptoms have long been recognized as a consequence of head injury. [12][13][14][15][16] Balance problems are among the most commonly reported chronic symptoms after mild head injury, such as a concussion, with an incidence ranging from 24% to 83%. [17][18][19] Peripheral vestibular symptoms following TBF are thought to be secondary to a number of causes: labyrinthine concussion, 20 perilymphatic fistula, 21 benign postural positional vertigo, 22 posttraumatic Ménière's syndrome, 23 or destruction of the vestibular membranous labyrinth.…”

Section: Introductionmentioning

confidence: 99%

Peripheral Vestibular Organ Degeneration After Temporal Bone Fracture: A Human Otopathology Study

et al. 2019

View full text Add to dashboard Cite

Objectives/Hypothesis Vestibular symptoms are a common sequela of temporal bone fractures (TBFs). The mechanisms of injury to the peripheral vestibular system following TBF, however, are not well described. Herein, we aimed to investigate the histopathology of the peripheral vestibular system in patients who sustained TBFs. Study Design Retrospective human specimen analysis. Methods Specimens from the National Temporal Bone Pathology Registry with (cases) and without (controls) TBFs were evaluated. Specimens were analyzed by light microscopy for vestibular hair cell and/or dendritic degeneration, presence of endolymphatic hydrops, blockage of the endolymphatic duct, and number of Scarpa ganglion cells (ScGCs) in the superior and inferior vestibular nerves. Results Seven temporal bones (TBs) from five individuals with TBFs, and seven TBs from six age‐matched individuals without a history of head injury met inclusion and exclusion criteria. All fractures involved the otic capsule. Severe degeneration of the cristae was identified in the semicircular canals in all TBF cases. The utricular and saccular maculae showed mild to severe degeneration in the TBF cases. Vestibular hydrops (n = 2 TBs) and blockage of the endolymphatic duct (n = 3 TBs) were also present in the TBF cases. There was a decrease of 52.6% in the mean total ScGC count in the TBF cases (n = 3 TBs) compared to age‐matched controls (n = 7 TBs, P = .015). There was a mean loss of 53% of the ScGCs in the superior vestibular nerve and a mean loss of 52.3% of the ScGCs in the inferior vestibular nerve compared to age‐matched controls (P = .033 and P = .021, respectively). Conclusions In a cohort of patients with TBFs, there were distinct peripheral vestibular changes including reduction of ScGCs. Level of Evidence NA Laryngoscope, 130:752–760, 2020

show abstract

Head Injury

Strauss¹

1934

Arch NeurPsych

View full text Add to dashboard Cite

Traumatic Vestibular Diseases

Cited by 14 publications

References 0 publications

Peripheral Vestibular System Histopathologic Changes following Head Injury without Temporal Bone Fracture

Peripheral Vestibular System Histopathologic Changes following Head Injury without Temporal Bone Fracture

Peripheral Vestibular Organ Degeneration After Temporal Bone Fracture: A Human Otopathology Study

Head Injury

Contact Info

Product

Resources

About