The registry classified 7,428 patients as C80, 8,849 as C77-79, and 10,804 as C20. Compared to C20, the number of cases of C80 showed a statistically significant increasing trend with 3 increasing travel time to primary care. Risk also increased strongly with age, and deprivation.Results for C77-C79 were similar to those for C80, except that the travel time to primary care showed no effect. Considering all CUP alone, histological diagnosis significantly declined with travel time to the nearest hospital. There was no association with sex and the likelihood of histological diagnosis, but a marked decline with age, a downward trend with deprivation, and an increase when the nearest hospital was a cancer centre. These findings facilitate the understanding of factors associated with the group of patients that includes those with the least effective access to cancer services.