Travelers as Sentinels for Chikungunya Fever, Brazil

Chaves, Tânia; Pellini, Alessandra Cristina Guedes; Mascheretti, Melissa; Jahnel, Maria Teresa; Ribeiro, Ana Freitas; Rodrigues, Sueli Guerreiro; Vasconcelos, Pedro Fernando da Costa; Boulos, Marcos

doi:10.3201/eid1803.110838

Cited by 24 publications

(20 citation statements)

References 8 publications

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“…This mosquito‐borne virus, so‐named in the East African Makonde language for its ability to cause crippling arthralgia, has caused large outbreaks in multiple locations in Africa, Asia, and the Western Pacific in the past decade . Before its arrival in St Martin, few doubted that CHIKV would eventually emerge and take hold in the Western Hemisphere given the widespread presence of competent mosquito vectors and opportunities for the virus to be introduced through travel and commerce . The virus' subsequent swift spread from St Martin throughout the Caribbean and onto South and Central America has created considerable concern regarding its eventual extent and intensity of transmission in the Western Hemisphere and hence its potential impact on transfusion safety.…”

Section: Possible Mitigation Strategies To Reduce the Risk Of Chikv Tmentioning

confidence: 99%

Chikungunya virus: new risk to transfusion safety in the Americas

Petersen

Epstein

2014

Transfusion

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Section: Possible Mitigation Strategies To Reduce the Risk Of Chikv Tmentioning

confidence: 99%

Chikungunya virus: new risk to transfusion safety in the Americas

Petersen

Epstein

2014

Transfusion

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“…In fact, as CHIKV and DENV share the same mosquito vector species, epidemic waves caused by both viruses affect the same regions, and human coinfections may occur (9,10). Moreover, the intensification of intercontinental travel with recurrent returns of dozens of viremic CHIKV cases from affected areas-which may bypass the surveillance systems due to the clinical similarities to other viruses circulating in the Americas-exemplifies the vulnerability of this continent to CHIKV epidemics (11,12). Indeed, Brazil, Canada, the United States, French Guiana, and the French West Indies (Guadeloupe and Martinique) have reported several imported cases of CHIKV since its reemergence in 2004 (6,13).…”

Section: Hikungunya Virus (Chikv) Is An Alphavirus In the Familymentioning

confidence: 99%

High Level of Vector Competence of Aedes aegypti and Aedes albopictus from Ten American Countries as a Crucial Factor in the Spread of Chikungunya Virus

Vega-Rúa

Zouache

Girod

et al. 2014

J Virol

385

357

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Chikungunya virus (CHIKV) causes a major public health problem. In 2004, CHIKV began an unprecedented global expansion and has been responsible for epidemics in Africa, Asia, islands in the Indian Ocean region, and surprisingly, in temperate regions, such as Europe. Intriguingly, no local transmission of chikungunya virus (CHIKV) had been reported in the Americas until recently, despite the presence of vectors and annually reported imported cases. Here, we assessed the vector competence of 35 American Aedes aegypti and Aedes albopictus mosquito populations for three CHIKV genotypes. We also compared the number of viral particles of different CHIKV strains in mosquito saliva at two different times postinfection. Primarily, viral dissemination rates were high for all mosquito populations irrespective of the tested CHIKV isolate. In contrast, differences in transmission efficiency (TE) were underlined in populations of both species through the Americas, suggesting the role of salivary glands in selecting CHIKV for highly efficient transmission. Nonetheless, both mosquito species were capable of transmitting all three CHIKV genotypes, and TE reached alarming rates as high as 83.3% and 96.7% in A. aegypti and A. albopictus populations, respectively. A. albopictus better transmitted the epidemic mutant strain CHIKV_0621 of the East-Central-South African (ECSA) genotype than did A. aegypti, whereas the latter species was more capable of transmitting the original ECSA CHIKV_115 strain and also the Asian genotype CHIKV_NC. Therefore, a high risk of establishment and spread of CHIKV throughout the tropical, subtropical, and even temperate regions of the Americas is more real than ever.

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“…Curiously, numerous travel-related cases were detected in the US, Canada, French Guiana, Brazil, and the Caribbean between 2006 and 2010, yet no autochthonous cases were identified during this time frame. [63][64][65][66] The molecular characterization of the isolates from St Martin and Martinique revealed that the strains were of Asian genotype similar to those from Yap and the Philippines. 67 …”

mentioning

confidence: 96%

Chikungunya virus outbreak expansion and microevolutionary events affecting epidemiology and epidemic potential

Powers¹

2015

RRTM

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Chikungunya virus (CHIKV) is a mosquito-borne virus that is associated with severe and prolonged arthralgia. Starting in 2004, CHIKV reemerged in a series of outbreaks along the east coast of Africa and on several islands of the Indian Ocean. Over the subsequent 10 years, the virus spread throughout the globe and caused over three million cases. Molecular characterization of the genomes over time revealed changes that were associated with changes in epidemiology and transmission patterns. Monitoring and exploitation of these changes may lead to better understanding of viral movement and potential options for prevention and control.

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Travelers as Sentinels for Chikungunya Fever, Brazil

Cited by 24 publications

References 8 publications

Chikungunya virus: new risk to transfusion safety in the Americas

Chikungunya virus: new risk to transfusion safety in the Americas

High Level of Vector Competence of Aedes aegypti and Aedes albopictus from Ten American Countries as a Crucial Factor in the Spread of Chikungunya Virus

Chikungunya virus outbreak expansion and microevolutionary events affecting epidemiology and epidemic potential

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