Treating Uncontrolled Hypertension with <i>Hibiscus sabdariffa</i> When Standard Treatment Is Insufficient: Pilot Intervention

Al-Anbaki, Marwah; Nogueira, Renata Campos; Cavin, Anne-Laure; Al-Hadid, Mamdouh; Al-Ajlouni, Ibrahim; Shuhaiber, Liyan; Graz, Bertrand

doi:10.1089/acm.2019.0220

Cited by 11 publications

(9 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…77 Consumption of HS with adapted doses between 10-20 g daily for one month was associated with an improvement in both diastolic and systolic BP, even in patients simultaneously taking antihypertensive medications. 78 An interesting study showed that HS has cardioprotective and antihypertensive effects in vivo and agreed with the public belief that HS can be a valuable antihypertensive agent. Vitamin C and anthocyanin are the main antioxidant compounds in the HS plant.…”

Section: Viscum Albummentioning

confidence: 52%

Pharmaceutical properties of sour tea (Hibiscus sabdariffa), Toward an ideal treatment for Hypertension

Fazljou¹,

Kamyab²,

Namdar³

et al. 2021

Pharm Sci

View full text Add to dashboard Cite

High blood pressure is the main risk factor for cardiovascular disease and should be controlled primarily by changes in lifestyle, such as regular exercise, a low-salt diet, and weight loss in overweight or obesity. If lifestyle changes are not enough, many types of medications can be used to control high blood pressure; however, side effects constitute one of the most critical limitations of conventional medicines associated with high blood pressure. For this reason, the use of traditional and herbal medicines has been welcomed by the public for many years. Sour tea (Hibiscus sabdariffa) is one of the most suitable herbal medicines for hypertension. According to research results, sour tea has the same effect as conventional medicines without serious side effects. The present study introduces sour tea as a suitable herbal medicine for high blood pressure to provide readers of this article with a comprehensive understanding of the medicinal properties of sour tea for the treatment of hypertension and its effects on several other common diseases, including cancer.

show abstract

Section: Viscum Albummentioning

confidence: 52%

Pharmaceutical properties of sour tea (Hibiscus sabdariffa), Toward an ideal treatment for Hypertension

Fazljou¹,

Kamyab²,

Namdar³

et al. 2021

Pharm Sci

View full text Add to dashboard Cite

show abstract

“…In the study conducted in Jordan [10], we found that with HS decoction, 38% of participants reached target BP after 1 month. In the control group, one might expect 10%.…”

Section: Discussionmentioning

confidence: 88%

“…This has long-term public health implications as the impact of a 10 mmHg (systolic) or 5 mmHg (diastolic) BP decrease can lead to a 22% reduction in coronary heart disease and a 41% reduction in strokes [16]. At the end of the 4 weeks in a pilot intervention among refugees in Jordan, 38% of participants reached the target BP [10]. In the present study, using the same dose regimen and inclusion criteria, but with longer follow-up, larger group size, and inclusion of a control group, we observed a greater magnitude of BP decrease.…”

Section: Discussionmentioning

confidence: 99%

“…The verification was carried out by the resident botanist based on macroscopic observations. Nigerian HS was chosen in Baghdad because it is among the most affordable options in the market and material of the same origin was used in the previous study in Jordan [10].…”

Section: Plant Materialsmentioning

confidence: 99%

“…During the same study, a similar effect was observed in the three treatment groups: Tablets made of the dried powdered calyx, versus decoction, versus standard treatment. In a pilot study conducted with refugee in Jordan, use of HS decoction during 1 month as an adjuvant therapy for patients with uncontrolled hypertension, whether they also used standard medication or not, was associated with promising results: 38% reached the target blood pressure (BP) and 65% of them had systolic blood pressure (SBP) lowered by at least 10 mmHg [10].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention

Al-Anbaki¹,

Cavin²,

Nogueira³

et al. 2021

Plants

Self Cite

View full text Add to dashboard Cite

In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product.

show abstract

Insight into stability and degradation kinetics of Roselle (Hibiscus sabdariffa L.) flowers anthocyanin, effect of pH, heating, storage conditions, and co-pigment treatment

Saidji,

Malki,

Boukerche

et al. 2023

Biomass Conv. Bioref.

View full text Add to dashboard Cite

Treating Uncontrolled Hypertension with Hibiscus sabdariffa When Standard Treatment Is Insufficient: Pilot Intervention

Cited by 11 publications

References 13 publications

Pharmaceutical properties of sour tea (Hibiscus sabdariffa), Toward an ideal treatment for Hypertension

Pharmaceutical properties of sour tea (Hibiscus sabdariffa), Toward an ideal treatment for Hypertension

Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention

Insight into stability and degradation kinetics of Roselle (Hibiscus sabdariffa L.) flowers anthocyanin, effect of pH, heating, storage conditions, and co-pigment treatment

Contact Info

Product

Resources

About